Ahmed, S., Sutalo, I.D., Kavnoudias, H. and Madan, A. (2007) Fluid Structure Interaction Modeling of a Patient Specific Cerebral Aneurysm: Effect of Hypertension and Modulus of Elasticity. 16th Australasian Fluid Mechanics Conference, Crown Plaza, 2-7 December 2007, 75-81.

has been cited by the following article:

• TITLE: Effects of Elasticity on Wall Shear Stress in Patient-Specific Aneurysm of Cerebral Artery

  AUTHORS: Ryuhei Yamaguchi, Taihei Kotani, Gaku Tanaka, Simon Tupin, Kahar Osman, Nadia Shaira Shafii, Ahmad Zahran Md Khudzari, Kazuhiro Watanabe, Hitomi Anzai, Atsushi Saito, Makoto Ohta

  KEYWORDS: Cerebral Aneurysm, Elasticity, Particle Image Velocimetry, Wall Shear Stress

  JOURNAL NAME: Journal of Flow Control, Measurement & Visualization, Vol.7 No.2, February 19, 2019

  ABSTRACT: The behavior of wall shear stress (WSS) was previously reported in a deformable aneurysm model using fluid-structure interactions. However, these findings have not been validated. In the present study, we examined the effect of elasticity (i.e., deformation) on wall shear stress inside a cerebral aneurysm at the apex of a bifurcation using particle image velocimetry in vitro. The flow model simulated a human patient-specific aneurysm at the apex of the bifurcation of the middle cerebral artery. Flow characteristics by wall elasticity were examined for both elastic and non-deformable aneurysm models with pulsatile blood flow. The absolute temporally- and spatially-averaged WSS along the bleb wall was smaller in the elastic model than that in the non-deformable model. This small WSS may be related to attenuation of the WSS. Further, the WSS gradient had a finite value near the stagnation point of the aneurysm dome. Finally, the WSS gradient near the stagnation point was slightly smaller in the elastic model than that in the non-deformable model. These data suggest that elasticity of the aneurysm wall can affect the progression and rupture of aneurysms via hemodynamic stress.