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https://doi.org/10.1371/journal.pone.0053708

has been cited by the following article:

• TITLE: The 3D Cell Culture System in the Study of Tumor-Applications and Prospects

  AUTHORS: Huizhen Yang, Jiaqi Jiao

  KEYWORDS: 3D Cell Culture System, 2D Cell Culture System, In Vitro Tumors

  JOURNAL NAME: Journal of Biosciences and Medicines, Vol.6 No.9, September 14, 2018

  ABSTRACT: Compared with 2D tumor cell culture, 3D tumor cell culture can better simulate the microenvironment of signal transduction between cells and extracellular matrix. As one of the best cell models in tumor research, it has been widely used in the study of cancer cell morphology, nanotechnology drug delivery system, and anticancer drug screening. The main theme of this paper is to review the previous research of 3D cell culture applying to tumors in vitro and the prospects for the applications of 3D cell culture system.