Eilbracht, P., Barfacker, L., Buss, C., Hollmann, C., Kitsos-Rzychon, B.E., Kranemann, C.L., Rische, T., Roggenbuck, R. and Schmidt, A. (1999) Tandem Reaction Sequences under Hydroformylation Conditions: New Synthetic Applications of Transition Metal Catalysis. Chemical Reviews, 99, 3329-3365.
https://doi.org/10.1021/cr970413r

has been cited by the following article:

• TITLE: Safe Hydroformylation of Aliphatic Alkene in a Flow Reactor

  AUTHORS: Hisashi Masui, Eiki Honda, Sakura Niitsu, Mitsuru Shoji, Takashi Takahashi

  KEYWORDS: Hydroformylation, Flow Synthesis, Alkene, Carbon Monoxide, Aldehyde

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.8 No.1, March 9, 2018

  ABSTRACT: Despite hydroformylation being a very efficient method for the transformation of alkenes, it is not commonly employed in laboratories owing to the flammable/toxic nature of hydrogen and carbon monoxide gases and the necessity of high-pressure equipment in a batch system. Flow chemistry often raises the safety profiles against high-pressure and toxic gases because the diameter of the flow reactor is small. Herein, we show that aliphatic alkenes can be safely hydroformylated in a flow reactor. In our flow method, although the target hydroformylated product was obtained in a low yield (19%), toxic gases were safely treated using a flow reactor. Better yields could possibly be achieved by recycling of the unreacted alkene.