TITLE:
Evaluation of Cardiovascular Risk Factors in a Young Adults Tunisian Group
AUTHORS:
Lamine Oussama, Aboulkacem Sana, Grira Nedra, Ayoub Manel, Sendesni Rihab, El Oudi Mabrouka, Stambouli Nejla, Mazigh Chakib, Aouni Zied
KEYWORDS:
Young Adult, Dyslipidemia, Cardiovascular Risk, Cholesterolemia
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.6 No.3,
March
7,
2018
ABSTRACT: Introduction: Cardiovascular
diseases have become more common in young adults. Their emergence is due to the
prevalence of cardiovascular risk factors. The aim of this study is to
determine the prevalence of cardiovascular risk factors in a Tunisian young
adult group. Material and methods: This is an epidemiological study of
705 Tunisians volunteers, free from any cardiovascular pathology; who are
recruited at the Military Hospital of Tunis. Besides the classical
cardiovascular risk factors (obesity, dyslipidemia, smoking, alcohol…), we
evaluate the level of homocysteinemia and determined the C677T mutation of the
methylenetetrahydrofolate reductase (MTHFR) gene by PCR-RFLP method. Results
and conclusions: The mean age of our population is 28.25 ± 9.08 with a male
majority (83.8%). We have 43.8% obese subject or overweight, 54.3% smokers and
12.9% alcoholics. The lipid profile showed that 12.6% of the population had
hypercholesterolemia and 39.5% had hypoHDLemia, 7.9%
had a high lipoprotein(a) concentration. In our study population we found that
10.9% of subjects had an hs-CRP concentration greater than 3 mg/L. Genotyping
of the MTHFR gene revealed that 34% of young adults had a mutated genome (CT).
The results showed a significant correlation between different factors, such as
cholesterolemia and obesity. The prevalence of these risk factors showed the
severity of our young people’s health status and imposes a change in the way of
Tunisians life.