Article citationsMore>>
Chanthery, Y.H., Gustafson, W.C., Itsara, M., Persson, A., Hackett, C.S., Grimmer, M., et al. (2012) Paracrine Signaling through MYCN Enhances Tumor-Vascular Interactions in Neuroblastoma. Science Translational Medicine, 4, 115ra113.
https://doi.org/10.1126/scitranslmed.3002977
has been cited by the following article:
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TITLE:
N-Myc Inhibition: Advances in Neuroblastoma Treatment
AUTHORS:
Md Kamrul Hasan
KEYWORDS:
Neuroblastoma, N-Myc, PI3K/mTOR, PARP1, PD-L1, HAUSP
JOURNAL NAME:
CellBio,
Vol.6 No.3,
September
30,
2017
ABSTRACT: Neuroblastoma (NBL) is one
of the most common solid tumors and around 15% of cancer mortality in children.
Amplification of the N-Myc proto-oncogene is strongly correlated with
advanced disease and poor clinical outcome in NBL. Recent studies described
that ubiquitin-specific protease 7 (USP7; also known as HAUSP) interacts with
N-Myc, induces deubiquitination and subsequent stabilization of N-Myc that
in-turn potentiates N-Myc
function, and treatment with the HAUSP inhibitor (P22077) blocked such effects.
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