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has been cited by the following article:

• TITLE: Radio Pet Therapy of Healthy Wistar Rats with 64CuCl2 Labeled to 64Cu(AcAc)2 Supported in Functionalized TiO2 Nanoparticles

  AUTHORS: Tessy López, Juan C. Manrique-Arias, Paola Ramírez, Pamela Larraza, Francisco Rodríguez Reinoso

  KEYWORDS: PET Therapy, Nanoparticles, Functionalized Titania (F-Tio2), Titanium Acetylacetonate [Cu (AcAc)2], Cu(Acac)2/F-Tio2, PET Lesion Detection, Imaging

  JOURNAL NAME: Journal of Encapsulation and Adsorption Sciences, Vol.7 No.3, September 26, 2017

  ABSTRACT: In recent years Copper-64 in the chemical form of copper chloride ([64Cu]CuCl2) has been identified as a potential agent for PET imaging and radionuclide therapy. The aim of this research was to determine the biodistribution and the labeling of radio nanoparticle with 64CuCl2, the nanoparticles Cu(acac)2/F-TiO2 were mixed with 64CuCl2 (20-37 MBq), then the final solution was used to injected healthy Wistar rats to probe the absorption of nanoparticle inside tissue trough of the groups OH that are formed during the functionalization of the Cu(acac)2/F-TiO2. The “in vivo” evaluation after realize the images study in micro PET equipment, uptake of the radio-nanoparticle was observed in the digestive system in the healthy Wistar rats.