Article citationsMore>>
Brugières, L., Le Deley, M.C., Rosolen, A., Williams, D., Horibe, K., Wrobel, G., Mann, G., Zsiros, J., Uyttebroeck, A., Marky, I., Lamant, L. and Reiter, A. (2009) Impact of the Methotrexate Administration Dose on the Need for Intrathecal Treatment in Children and Adolescents with Anaplastic Large-Cell Lymphoma: Results of a Randomized Trial of the EICNHL Group. Journal of Clinical Oncology, 27, 897-903.
https://doi.org/10.1200/JCO.2008.18.1487
has been cited by the following article:
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TITLE:
Brentuximab Vedotin Monotherapy and Combined with Low Dose Donor Lymphocyte Infusion to Control Minimal Residual Disease and Sustain Clinical Remission in a Child with Relapsed Anaplastic Large Cell Lymphoma
AUTHORS:
Alina S. Fedorova, Maria V. Stegantseva, Nina V. Minakovskaya, Olga V. Aleinikova
KEYWORDS:
Anaplastic Large Cell Lymphoma, Relapse, Brentuximab Vedotin, Donor Lymphocyte Infusion, Minimal Residual Disease
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.8 No.8,
July
28,
2017
ABSTRACT: Minimal
residual disease (MRD) appears to have a strong negative predictive value for
disease recurrence in children with anaplastic large cell lymphoma (ALCL).
Brentuximab vedotin (BV) can be a therapeutic option for MRD-positive
patients to achieve molecular remission and to decrease risk of subsequent
relapse. We here report a 4-year-old child with ALCL progression during relapse
treatment who received BV as a bridging therapy before haploidentical
hematopoietic stem-cell transplantation, and as a maintenance therapy
post-transplant alone or combined with simultaneous low dose donor-lymphocyte
infusions. MRD monitoring showed a complete molecular response and reflected
both BV efficiency and graft-versus-lymphoma effect.
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