TITLE:
Effect of SRD-P401 on the Discomfort of Neck and/or Shoulder Stiffness
AUTHORS:
Akira Iizuka, Maasa Sonoda, Ruka Goto, Tokunori Matsui, Chiaki Kudoh, Katsumi Kido, Yasuhiro Komatsu
KEYWORDS:
Supplement, Anti-Inflammatory, Anti-Nociceptive, SRD-P401
JOURNAL NAME:
American Journal of Plant Sciences,
Vol.8 No.5,
April
26,
2017
ABSTRACT: SRD-P401 is a newly developed healthy food
supplement which has an anti-inflammatory and analgesic effect. In this report,
the effects of SRD-P401 on neck and shoulder stiffness were assessed by an inquiry method in the public
field. The stiffness symptoms of all participants were improved after taking
SRD-P401. The symptoms of the participants who took 3 g/day and/or 9 g/day of
SRD-P401 improved in a week after taking it. Unpleasant adverse effects in
stomach and alimentally organs were not found during the test period. SRD-P401
showed the anti-nociceptive effect on the acetic-acid-induces abdominal
writhing in rats. The potency was equivalent to aspirin. Moreover, to
investigate the ability of the anti-inflammatory effects of SRD-P401, we exerted
by inhibiting the Cyclooxygenase (COX) enzyme activity. SRD-P401 and its constituents
inhibit the COX activity. The results of this field test indicated SRD-P401 would
be a beneficial and useful healthy food supplement for a person with stiffness
in neck and/or shoulder.