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https://doi.org/10.3390/ijms150916484

has been cited by the following article:

• TITLE: Methylenetetrahydrofolate Reductase (MTHFR) Gene Mutations in Patients with Idiopathic Scoliosis: A Clinical Chart Review

  AUTHORS: Mark W. Morningstar, Megan N. Strauchman, Clayton J. Stitzel, Brian Dovorany, Aatif Siddiqui

  KEYWORDS: Genetics, MTHFR, Polymorphism, Methylation, Scoliosis, Spine

  JOURNAL NAME: Open Journal of Genetics, Vol.7 No.1, March 30, 2017

  ABSTRACT: The effects of genetic variations of methylenetetrahydrofolate reductase (MTHFR) enzyme activity have been the discussion of many research papers. It has been associated with multiple neurological sequelae, and has been implicated in other chronic diseases. Although many genetic influences on the development and/or progression of idiopathic scoliosis have been reported, there has been no report of any relationship between MTHFR mutations and idiopathic scoliosis. This paper compared two groups of patients who received MTHFR genetic testing. One group had a history of idiopathic scoliosis, while the other served as a control group. The scoliosis group showed a positive MTHFR mutation in 23 out of 44 patients, while the control group showed 11/44 (P