TITLE:
Microwave Irradiation Effect on the Ligand Exchange Reaction between Ferrocene and Heterocycles
AUTHORS:
Yutaka Okada, Atsushi Niou, Shinya Nakano
KEYWORDS:
Microwave Irradiation Effect, Ferrocene, Ligand Exchange, Heterocycle
JOURNAL NAME:
Green and Sustainable Chemistry,
Vol.7 No.2,
March
15,
2017
ABSTRACT: The ligand exchange reaction is a typical reaction
of ferrocenes. This reaction proceeds via the abstraction of a cyclopentadienyl
ring by a Lewis acid followed by coordination of an aromatic compound to the
resulting species. This reaction with conventional heating requires a long
reaction time. Furthermore, the reactions with heterocycles are lower than
those with the corresponding hydrocarbons, and do not produce any products in
some cases. In this paper, the ligand exchange reaction of ferrocene and a
heterocyclic aromatic compound during microwave irradiation and its effect are
discussed. As a result, for some heterocycles, the decrease in the reaction
time was confirmed. Furthermore, under the microwave irradiation conditions,
the tendency in which the difference in their reactivities became low was
confirmed.