TITLE:
Synthesis of Some New Bisindole Derivatives and Their Biological Activity
AUTHORS:
Amal S. Yanni
KEYWORDS:
Synthesis, Bisindoletetrones, Cycloaddition, Antimicrobial Activity
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.6 No.4,
November
11,
2016
ABSTRACT: Pyrrolidines are well known for their versatile pharmacological activities such as antimicrobial [1] [2] [3] [4], antitumor [5], anti HIV [6], anticonvulsant [7] [8], human melanocortin-4 receptor agonists [9], etc. Moreover, indole nucleus is an important element of many natural and synthetic molecules that covers some of the relevant and recent achievement in the biological, chemical and pharmaceutical activity of important indole derivatives [10]. In view of these observations, the intention is directed to synthesize some new bisindole derivatives of expected biological interest.