TITLE:
In Vitro Anthelmintic Activity of Mucuna pruriens (DC) and Canarium schweinfurthii (Engl) on Ascaris suum
AUTHORS:
B. J. Okoli, R. G. Ayo, J. D. Habila, S. L. Japhet, G. I. Ndukwe
KEYWORDS:
Anthelmintic Activity, Mucuna pruriens, Canarium schweinfurthii, Pheretima posthuma, A. suum, Eclodibility
JOURNAL NAME:
Open Access Library Journal,
Vol.2 No.2,
February
2,
2015
ABSTRACT:
The in vitro anthelmintic evaluation of the
crude extracts and solvent partitions on Pheretima posthuma and Ascarissuum (eggs and L2 stage) respectively showed significant results at the same
concentration (10, 20, 40 and 80 mg/ml). This study
provides a clear evidence for usage of Mucuna pruriens and Canarium schweinfurthii as an anthelmintic. The most
potent ovicidal partition of C. schweinfurthii (Engl) leaves and bark and leaves
of M. pruriens (DC) is hexane (100.00 ± 0.33), chloroform (98.20 ± 0.12) and chloroform (98.70 ± 0.88)
partitioned crude respectively at 80 mg/ml while the most potent larvicidal partition is hexane (0.06%), chloroform
(0.1%) and chloroform (0.2%). The active compounds are predominantly in
the non-polar solvent which supports the tegumental diffusing activity of the
compounds.