TITLE:
The Effect of Intramuscular versus Intra-Amniotic Dexamethasone Administration on Blood Glucose Level in Diabetic Pregnant Women
AUTHORS:
Yuchun Zhu, Xinran He, Fang Yan, Yu Sun
KEYWORDS:
Antenatal Corticosteroids, Dexamethasone, Blood glucose, Diabetes Mellitus, Pregnancy
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.6 No.7,
June
21,
2016
ABSTRACT: Background: To investigate the blood glucose level response of diabetic
pregnant women when administrating antenatal dexamethasone to accelerate fetal
lung maturity in different routes. Methods: This prospective cohort study
included 60 pregnant women with diabetes who required promotion of fetal lung
maturity in Peking University First Hospital from January 2013 to April 2015.
Dexamethasone was administered by IM (n = 29) or IAC (n = 31). Blood glucose
level was monitored before injection, and 1 day, 2 days and 3 days after
injection. Results: In the intramuscular injection group, the preprandial and
postprandial blood glucose concentration was significantly elevated in
the first two days (P significantly elevated on the first day (P