TITLE:
Amyloidogenic Pituitary Prolactinoma
AUTHORS:
Pidakala Premalatha, Inuganti Venkata Renuka, Thumma Rayapa Reddy, Akula Meghana
KEYWORDS:
Pituitary Adenoma, Prolactinoma, Amyloid
JOURNAL NAME:
International Journal of Otolaryngology and Head & Neck Surgery,
Vol.5 No.3,
May
31,
2016
ABSTRACT: Prolactinomas are the most common benign pituitary neoplasms and the common cause of hyperprolactinemia.
Most of them arise in women of reproductive age. In men, they are often functionally
silent, but present with manifestations secondary to pressure effects when they become macro
adenomas. We present a case of prolactinoma in a 54-year old male patient who presented
with pressure effects because of the tumor, as head ache and bi-temporal hemianopsia. MRI Brain
scan was done to identify the tumor. The patient underwent trans-sphenoidal resection of the pituitary
macro adenoma. Histological examination revealed spheroid amyloid deposits, almost replacing
the adenoma. No medical treatment was given but the tumor recurred after 6 months and
a repeat surgery was done for total excision.