Stagos, D., Kazantzoglou, G., Theofanidou, D., Kakalopoulou, G., Magiatis, P., Mitaku, S. and Kouretas, D. (2006) Activity of Grape Extracts from Greek Varieties of Vitis vinifera against Mutagenicity Induced by Bleomycin and Hydrogen Peroxide in Salmonella typhimurium Strain TA102. Mutation Research, 609, 165-175. http://dx.doi.org/10.1016/j.mrgentox.2006.06.032

has been cited by the following article:

• TITLE: Antimutagenic and DNA Damage Protective Activities of a Grape Extract from Vitis vinifera

  AUTHORS: Zuzana Rybková, Kateřina Malachová, Jiří Červeň, Hana Sezimová, Petr Pečinka

  KEYWORDS: Ames Test, Antimutagenicity, Free Radical Scavenging, DNA Strand Scission, Vitis vinifera

  JOURNAL NAME: Journal of Biosciences and Medicines, Vol.4 No.6, May 24, 2016

  ABSTRACT: Antimutagenic and DNA protective effect of an extract VinOserae from Vitis vinifera grapes on oxidative DNA damage was investigated. The extract’s ability to inhibit mutagenicity induced by tert-butyl hydroperoxide (t-BHP) and hydrogen peroxide (H2O2) was determined with Ames test using Salmonella typhimurium His? TA102 strain. Inhibition values of 44.2% and 67.0% were detected for t-BHP and H2O2, respectively. A protective ability of the extract against DNA strand scission induced by hydroxyl radicals was studied with plasmid pBluescript II SK(-). The analysis of DNA strand breaks in plasmid DNA showed a significant inhibition of DNA damage.