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has been cited by the following article:

• TITLE: Rare Aggressive Form of Multiple Myeloma with Diffuse Osteosclerosis and Elevated CA 15-3 Levels

  AUTHORS: Dally Najib, Daniel Talmud, Saher Srour, Rola Khamisy-Farah, Raymond Farah

  KEYWORDS: Multiple Myeloma, Osteosclerosis, CA 15-3, Pleural Effusion

  JOURNAL NAME: Open Journal of Internal Medicine, Vol.6 No.1, March 25, 2016

  ABSTRACT: We report the case of a 56-year-old female who had recently been examined for back and epigastric pain, and was diagnosed in the internal medicine ward as having an aggressive rare form of multiple myeloma with diffuse osteoblastic bone lesions. She also had high levels of breast tumor marker (CA 15-3), severe tumor lysis syndrome, and pleural and central nervous system involvement. A few cases of multiple myeloma with diffuse osteosclerosis that are not part of POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, skin changeshave) have been described. None of these cases were as aggressive as our case. To our knowledge it is the first report describing an elevation in CA 15-3 in conjunction with multiple myeloma.