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has been cited by the following article:

• TITLE: Hepatic Sinusoidal Obstruction Syndrome without Preceding Medical Events

  AUTHORS: Yukino Kawanami, Riko Kitazawa, Ryuma Haraguchi, Yasuo Ueda, Yukiko Nishi, Kanazu Ariyasu, Yosuke Mizuno, Sohei Kitazawa

  KEYWORDS: Sinusoidal Obstruction Syndrome, CD34, Sinusoidal Capillarization

  JOURNAL NAME: Case Reports in Clinical Medicine, Vol.5 No.3, March 17, 2016

  ABSTRACT: Sinusoidal obstruction syndrome (SOS) is one of the severe complications of radiation, anticancer chemotherapy and immunosuppressive agents for transplantation. Autopsy of a case of rapidly progressive, uncontrollable severe ascites, without apparent signs of preceding drug toxicity, revealed a tensely enlarged liver and spleen, and 3000 ml of ascites attributed to secondary portal hypertension. Histopathological analysis disclosed sinusoidal endothelial damage and fibrous expansion from central veins. All the foregoing indicated hepatic SOS that needs to be included in the differential diagnosis of progressive ascites in patients without an apparent history of malignancy or transplantation.