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has been cited by the following article:

• TITLE: Tumour Associated Tissue Eosinophilia as a Prognostic Indicator in Squamous Cell Carcinoma of Upper Aerodigestive Tract

  AUTHORS: Chandra Bhan, Kartikeya Purohit, Jagdish Prasad Purohit, Ajay Pratap Singh, Bhoopendra Singh, Siva Selvaraj, Manish Pandey, Vineet Kumar, Vineet Kumar

  KEYWORDS: Tumour Associated Tissue Eosinophilia (TATE), Squamous Cell Carcinoma (SCC)

  JOURNAL NAME: International Journal of Otolaryngology and Head & Neck Surgery, Vol.5 No.2, March 8, 2016

  ABSTRACT: Immune response is known to develop against malignant tumours. Malignant tumours express newer antigen on their cell surface membrane which elicit immunological reaction in and around tumoural tissue. In early part of immune reaction neutrophil, eosinophil migrates followed by monocyte-macrophage cell. Tumor associated tissue eosinophilia (TATE) is believed to play a significant role in the biological behavior of the carcinoma. Eosinophil infiltrate in association with the head and neck squamous cell carcinoma (SCC) have been reviewed from time-to-time. The significance of such an association has been variably thought to be either a potential diagnostic tool for stromal invasion or as a prognostic indicator. The aim of this study was to investigate and evaluate the possible role of the tumour associated tissue eosinophilia (TATE) as a predictive indicator for the grading and establishing prognosis of the upper aerodigestive tract squamous cell carcinoma (SCC).