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http://dx.doi.org/10.1248/yakushi.127.193

has been cited by the following article:

• TITLE: Determination of Meclofenoxate Content in Meclofenoxate Hydrochloride for Injection by DSC and 1H-NMR

  AUTHORS: Peipei Zhang, Tingting Liu, Xuejiao Xu, Shuyu Liu, Dongying Chen

  KEYWORDS: Meclofenoxate Hydrochloride, DSC, 1H-NMR, Analysis

  JOURNAL NAME: American Journal of Analytical Chemistry, Vol.7 No.1, January 25, 2016

  ABSTRACT: Two simple and rapid analytical methods (DSC and 1H-NMR), are proposed for determination of meclofenoxate in meclofenoxate hydrochloride for injection. DSC thermogram is recorded without any sample pretreatment. The response linearity is ensured by linear determination factors R2, which is 0.9982. The recoveries of meclofenoxate hydrochloride in sterile powder for injection are from 98.3% to 102.3% (n = 3). The quantitative 1H-NMR is quick and simple to use. The quantitation of meclofenoxate is reproducible and the relative standard deviation is 1.0%. The accuracy of two methods is validated by comparison with the results obtained by HPLC. The results show that the two methods are capable of quantifying the content of meclofenoxate in meclofenoxate hydrochloride for injection.