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has been cited by the following article:

• TITLE: Comparative Analysis of Adaptive Vessel Segmentation—Cerebral Arteriovenous Malformation

  AUTHORS: Yadalam Kiran Kumar, Shashi Bhushan Mehta, Manjunath Ramachandra

  KEYWORDS: Adaptive Segmentation, AVM, Lumped Model

  JOURNAL NAME: Journal of Biomedical Science and Engineering, Vol.8 No.12, December 17, 2015

  ABSTRACT: Aim: Neurovascular abnormalities are extremely complex, due to the multitude of factors acting simultaneously on cerebral hemodynamics. Cerebral Arteriovenous Malformation (CAVM) hemo-dynamic in one of the vascular abnormality condition results changes in the vessels structures and hemodynamics in blood vessels. The challenge is segmenting accurate vessel region to measure hemodynamics of CAVM patients. The clinical procedure is in-vivo method to measure hemodynamics. The catheter-based procedure is difficult, as it is sometimes difficult to reach vessels sub-structures. Methods: In this paper, we have proposed adaptive vessel segmentation based on threshold technique for CAVM patients. We have compared different adaptive methods for vessel segmentation of CAVM structures. The sub-structures are modeled using lumped model to measure hemodynamics non-invasively. Results: Twenty-three CAVM patients with 150 different vessel locations of DSA datasets were studied as part of the adaptive segmentation. 30 simulated data has been evaluated for more than 150 vessels locations for sub-segmentation of vessels. The segmentation results are evaluated with accuracy of 93%. The computed p-value is smaller than the significance level 0.05. Conclusion: The adaptive segmentation using threshold based produces accurate vessel segmentation, results in better accuracy of hemodynamic measurements for DSA images for CAVM patients. The proposed adaptive segmentation helps clinicians to measure hemodynamic non-invasively for the segmented sub-structures of vessels.