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Breedveld, F.C., Weisman, M.H., Kavanaugh, A.F., Cohen, S.B., Pavelka, K., van Vollenhoven, R., et al. (2006) The PREMIER Study—A Multicenter, Randomized, Double-Blind Clinical Trial of Combination Therapy with Adalimu- mab plus Methotrexate versus Methotrexate Alone or Adalimumab Alone in Patients with Early, Aggressive Rheu- matoid Arthritis Who Had Not Had Previous Methotrexate Treatment. Arthritis & Rheumatism, 54, 26-37. http://dx.doi.org/10.1002/art.21519

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