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http://dx.doi.org/10.1021/cg400529s

has been cited by the following article:

• TITLE: Solventless Organic Reactive Crystallization at Mild Conditions

  AUTHORS: Masaaki Yokota, Norihito Doki, Hiroyuki Akagaki

  KEYWORDS: Reaction, Crystallization, Polymorphism, Dehydration Condensation

  JOURNAL NAME: Advances in Chemical Engineering and Science, Vol.5 No.4, October 12, 2015

  ABSTRACT: Solid state mixtures of two reactants, 2-hydroxy-1-naphthaldehyde and 2-aminobenzonitrile, were melted at a temperature even lower than both the melting points. And dehydration condensation reaction occurred in the melt to give reaction product N-(2-cyanophenyl)-2-hydroxy-1-naphthadimine. Since the melting point of the product was higher than the reactants, self-crystallization of the product occurred. Usefulness of this one-pot synthesis and crystallization method for industrial application was described.