TITLE:
One Day Polyethylene Glycol-3350 for Bowel Preparation in Pediatrics: A Literature Review
AUTHORS:
Shristi Shakya, Sumisti Shakya, Zhongyue Li
KEYWORDS:
Bowel Preparation, One Day Preparation, Pediatrics, PEG-3350
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.5 No.3,
September
23,
2015
ABSTRACT: Bowel preparation for colonoscopy in children is a challenging procedure.
Wide variety of preparation protocols exist, varying with the hospital. Unlike
in adults, there is a lack of uniform bowel preparation protocol in children.
Ideally, the bowel preparation agents are assessed by their safety, efficacy
and tolerability. Unfortunately, none of the preparations currently available
meets all of these criteria. However, since last decade, Polyethylene
Glycol-3350 (PEG-3350) is gaining popularity for bowel preparation with
reported safety, efficacy, and tolerability. The only major drawback of PEG-3350
without electrolyte was 4 days long preparation time thus raising the question
if the duration of preparation time could be minimized and yet have same
efficacy, safety, and tolerability of the medicine. Hence, one day PEG-3350
regimen was introduced eventually and is now being studied with increased
dosage or combined with other laxatives. This is the first review which
compiles the study so far conducted on one day PEG-3350 without electrolyte as
colonoscopy bowel preparation in children and tries to summaries if this
regimen can be commonly used in children for colonoscopy bowel preparation.