TITLE:
Which Disease and Individual-Based Factors Predict Intentions to Undergo Whole Genome Sequencing?
AUTHORS:
Felicity Kiln, Alana Fisher, Ilona Juraskova
KEYWORDS:
Whole Genome Sequencing, Disease Penetrance, Treatment Availability, Psychological Factors, Theoretical Model
JOURNAL NAME:
International Journal of Clinical Medicine,
Vol.5 No.20,
November
4,
2014
ABSTRACT: Purpose: The past decade has seen rapid acceleration in the public’s access to Whole Genome Sequencing (WGS) technology, however, factors that may influence a person’s decision to undergo this complex health screening have received little empirical attention. This is the first psychosocial study to investigate which disease and individual-based factors predict intention to undergo WGS. Methods: A total of 164 first-year university students responded to hypothetical disease scenarios (varied by disease penetrance and treatment availability) and completed self-report measures of individual factors. Results: Intention to undergo WGS was significantly higher in the presence of available treatment and high disease penetrance (p p p