TITLE:
The Centricity Score: A Novel Measurement to Aid in Conservative Breast Cancer Surgery
AUTHORS:
Ryan Sugrue, Katherine McGowan, Cillian McNamara, Michael Sugrue
KEYWORDS:
Breast Cancer, Wide Local Excision, Positive Margins, Re-Excision Rates, Specimen Radiography
JOURNAL NAME:
Advances in Breast Cancer Research,
Vol.3 No.4,
October
22,
2014
ABSTRACT: Introduction: This study
describes an intra-operative scoring system to advise the surgeon of thecentricity of the tumour in the
excised specimen. Methods: Spatial estimations were prospectively made in 10
consecutive patients undergoing wide local excision (WLE) using Bioptics
intra-operative digital specimen imaging. The centricity score was defined as
100 – (ICD/SD×100), where ICD is the inter-centre
distance between the specimen’s centre and the tumour’s centre. Results: 10
patients with invasive breast cancer (T1b to T4a), mean age 56 years (range 44
- 71) were studied. The mean tumour and specimen diameter was 24 mm ± 10 (range
12 - 48) and 101 mm ± 22 (range 64 - 140). The mean centricity score was 86 ± 9
(range 65 - 95). Conclusion:This
study successfullydescribes an
intraoperative radiological spatial scoring system for patients undergoing WLE.
Tumours were well centered in specimens with an overall score of 86/100. The
centricity score couldbe used to
guide excision and potentially set benchmarks for conservative breast surgery.