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Lopera, F., Ardilla, A., Martinez, A., Madrigal, L., Aran- go-Viana, J.C., Lemere, C.A., et al. (1997) Clinical features of early-onset Alzheimer disease in a large kindred with an E280A presenilin-1 mutation. JAMA, 277, 793-799. http://dx.doi.org/10.1001/jama.1997.03540340027028

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