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Author(s): |
Can Zhang, Hubei Key Laboratory of Genetic Regulation and Integrative Biology, College of Life Sciences, Hua Zhong Normal University, Hubei，Wuhan, China
Xue Yang, Hubei Key Laboratory of Genetic Regulation and Integrative Biology, College of Life Sciences, Hua Zhong Normal University, Hubei，Wuhan, China
Zhen He, Hubei Key Laboratory of Genetic Regulation and Integrative Biology, College of Life Sciences, Hua Zhong Normal University, Hubei，Wuhan, China
Wen Mu, Hubei Key Laboratory of Genetic Regulation and Integrative Biology, College of Life Sciences, Hua Zhong Normal University, Hubei，Wuhan, China
Qiaoqiao Zhou, Hubei Key Laboratory of Genetic Regulation and Integrative Biology, College of Life Sciences, Hua Zhong Normal University, Hubei，Wuhan, China
Xiaojing Hu, Hubei Key Laboratory of Genetic Regulation and Integrative Biology, College of Life Sciences, Hua Zhong Normal University, Hubei，Wuhan, China
Li Xiong, Hubei Key Laboratory of Genetic Regulation and Integrative Biology, College of Life Sciences, Hua Zhong Normal University, Hubei，Wuhan, China
Deli Liu, Hubei Key Laboratory of Genetic Regulation and Integrative Biology, College of Life Sciences, Hua Zhong Normal University, Hubei，Wuhan, China |
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Abstract: |
This study evaluated the effect of butyl benzyl phthalate(BBP), an important class of environmental endocrine disruptors on SOD、AChE、CAT of Danio rerio. Based on the BBP LC50, zebrafish were exposed to different BBP concentrations (0、0.332、0.665、1.33 mg·L-1). The activities were determined in the fish collected at 7d, 14d, 21d and 28d post-exposure. It showed that as the extension of time and the exposure concentrations, from 0d to 28d, the AChE activity was significantly inhibited. The SOD activity increased firstly and then declined with time extension. The CAT activity, in 7d, except 0.665 mg ? L-1 group was inhibited significantly (p < 0.01), the rest groups were of no significant difference compared with the control. At 14d, except 0.332 mg ? L-1 group, which was always higher than the control, it showed a downward trend after the first rise for other groups; for 28d, the CAT activity of each treated group showed induction effect compared with the control.
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