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Title: |
Effect of Microwave Radiation at 2450MHz on the Oxidative Damage to the Mice Liver |
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Source: |
Conference on Environmental Pollution and Public Health (CEPPH 2010 E-BOOK)
(pp 251-254)
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Author(s): |
Yubin Ji, Center for Life Sciences and Environmental Sciences, Harbin University of Commerce, Harbin 150076/Institute of Materia Medica and Postdoctoral Program of Harbin University of Commerce，Harbin 150076/Engineering Research Center of Natural Anticancer Drugs，
Lintao Liu, Center for Life Sciences and Environmental Sciences, Harbin University of Commerce, Harbin 150076/Engineering Research Center of Natural Anticancer Drugs，Ministry of Education, Harbin 150076
Lei Yu, Center for Life Sciences and Environmental Sciences, Harbin University of Commerce, Harbin 150076/Institute of Materia Medica and Postdoctoral Program of Harbin University of Commerce，Harbin 150076/Engineering Research Center of Natural Anticancer Drugs， |
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Abstract: |
To study the effect of the microwave radiation on the activities of superoxide dismutase (SOD) and catalase (CAT), as well as the contents of glutathione (GSH) and malondialdehyde (MDA) in the mice liver. Under the microwave frequency at 2450MHz, the lab mice were divided into four groups, including one blank control group, three other groups with radiation power density of 10mW/cm2, 20mW/cm2, and 40mW/cm2, respectively. Each group was irradiated for 2 hours each day in one month. Activities of SOD and CAT in the liver were determined using NBT hydroxylamine method and ultra-violet spectrophotometry, respectively; meanwhile, contents of MDA and GSH were determined using TBA and DTNB development processes. The activity of SOD increased compared with that of the blank control group, in which a significant increase was observed corresponding to the group with 40mW/cm2 irradiation. The contents of MDA and GSH both increased significantly, while the activity of CAT showed no obvious difference, but declined instead. The microwave radiation at frequency of 2450MHz can cause the oxidative stress in the mice liver, resulting in some certain damages.
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