Surgical Technique Used for Portal Vein Thrombosis when Thrombectomy Is Not Possible During Liver Transplantation

Abstract

Portal vein thrombosis (PVT) was for a long time considered a barrier to liver transplantation. The aim of this study is to demonstrate the surgical technical options for portal vein reconstruction during liver transplantation in patients with PVT in which thrombectomy was not possible. Between September 1991 and March 2009, 420 liver transplanted patients were retrospectively analyzed, identifying 29 cases with PVT (6.9%). Preoperative diagnosis, preoperative risk factors, surgical technique options to treat various forms (grades) of PVT, postoperative recurrence and actuarial survival rates were studied. In three cases of PVT grade II and in one case PVT grade III the thrombectomy was insufficient, requiring some surgical technique options (13.79%). In two cases placement of iliac vein graft was performed, in one an anastomosis of the portal vein with collateral splenorenal vein and in the other with left gastric varicose. The actuarial survival rate for patients without PVT and patients with PVT and effective thrombectomy was 73.8% while those with PVT who needed some type of surgical option was 75%. Our results suggest that actuarial survival rates were similar among patients with PVT or PVT with effective thrombectomy when compared with PVT that required some surgical options.

Share and Cite:

J. Alves, I. Boin, A. Ramos, C. Reigada, N. Caserta, A. Cardoso, C. Caruy, E. Ataíde and J. Almeida, "Surgical Technique Used for Portal Vein Thrombosis when Thrombectomy Is Not Possible During Liver Transplantation," Surgical Science, Vol. 2 No. 5, 2011, pp. 248-251. doi: 10.4236/ss.2011.25055.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] M. Ogren, D. Bergqvist, M. Bjorck, S. Acosta, H. Eriks-sonet and N. H. Sternby, “Portal Vein Thrombosis: Pre-valence, Patient Characteristics and Lifetime Risk—A Population Study Base on 23796 Consecutive Autopsies,” World Journal of Gastroenterol, Vol. 12, No. 13, 2006, pp. 2115-2119.
[2] J. Hoekstra and H. L. A. Janssen, “Vascular Liver Disorders: Portal Vein Thrombosis,” Netherlands Journal of Medicine, Vol. 67, No. 2, 2009, pp. 46-52.
[3] J. Lendoire, G. Raffin, N. Cejas, F. Duek, P. Barros Schelotto, P. Trigo, et al., “Liver Transplantation in Adult Patients with Portal Vein Thrombosis: Risk Factors, Ma- nagement and Outcome,” The Official Journal of the International Hepato Pancreato Biliary, Vol. 9, No. 5, 2007, pp. 352-356.
[4] R. Charco, et al., “Portal Vein Thrombosis in Liver Transplantation,” Transplantation Proceedings, Vol. 37, No. 9, 2005, pp. 3904-3905. doi:10.1016/j.transproceed.2005.09.120
[5] M. A. Yerdel, et al., “Portal Vein Thrombosis in Adults Undergoing Liver Transplantation,” Transplantation, Vol. 69, No. 9, 2000, pp. 1873-1881. doi:10.1097/00007890-200005150-00023
[6] Y. F. Tao, et al., “Liver Transplant Recipients with Portal Vein Thrombosis: A Single Center Retrospective Study,” Hepatobiliary & Pancreatic Diseases International, Vol. 8, No. 1, 2009, pp. 34-39.
[7] R. Robles, et al., “Eversion Thromboendovenectomy in Organized Portal Vein Thrombosis during Liver Trans-plantation,” Clinical Transplantation, Vol. 18, No. 1, 2004, pp. 79-84. doi:10.1111/j.1399-0012.2004.00120.x
[8] M. Paskonis, et al., “Surgical Strategies for Liver Trans-plantation in the Case of Portal Vein Thrombosis – Current Role of Cavoportal Hemitransposition and Renoportal Anastomosis,” Clinical Transplantation, Vol. 20, No. 5, 2006, pp. 551-562. doi:10.1111/j.1399-0012.2006.00560.x
[9] C. Pan, et al., “Single-Center Experience of 253 Portal Vein Thrombosis Patients Undergoing Liver Transplanta-tion in China,” Transplantation Proceedings, Vol. 41, No. 9, 2009, pp. 3761-3765. doi:10.1016/j.transproceed.2009.06.215
[10] L. Lladó, et al., “Management of Portal Vein Thrombosis in Liver Transplantation: Influence on Morbidity and Mortality,” Clinical Transplantation, Vol. 21, No. 6, 2007, pp. 716-721.
[11] D. Nikitin, et al., “Twenty Years’ Follow-Up of Portal Vein Conduits in Liver Transplantation,” Liver Trans-plantation, Vol. 5, No. 4, 2009, pp. 400-406. doi:10.1002/lt.21698
[12] J. Dumortier, et al., “Eversion Thrombectomy for Portal Vein Thrombosis During Liver Transplantation,” Ameri-can Journal of Transplantation, Vol.2, No.10, 2002, pp. 934-938. doi:10.1034/j.1600-6143.2002.21009.x
[13] A. Tzakis, S. Todo and T. E. Starzl, “Orthotopic Liver Transplantation with Preservation of the Inferior Vena Cava,” Annals of Surgery, Vol. 21, No. 6, 1989, pp. 649-652. doi:10.1097/00000658-198911000-00013
[14] G. Manzanet, et al., “Liver Transplantation in Patients with Portal Vein Thrombosis,” Liver Transplantation, Vol. 7, No. 2, 2001, pp. 125-131. doi:10.1053/jlts.2001.21295
[15] A. C. Stieber, et al., “The Spectrum of Portal Vein Thrombosis in Liver Transplantation,” Annals of Surgery, Vol. 213, No. 3, 1991, pp. 199-206. doi:10.1097/00000658-199103000-00003
[16] B. R. Davidson, M. Gibson, R. Dick, A. Burroughs and K. Rolles, “Incidence, Risk Factors, Management, and Out-come of Portal Vein Abnormalities at Orthotopic Liver Transplantation,” Transplantation, Vol. 57, No. 8, 1994, pp. 1174-1177. doi:10.1097/00007890-199404270-00006
[17] R. Quarrie and S. P. Stawicki, “Portal Vein Thrombosis: What Surgeons Need to Know,” OPUS 12 Scientist, Vol. 2, No. 3, 2008, pp. 30-33.
[18] B. Pérez-Saborido, et al., “Incidence, Management, and Results of Vascular Complications after Liver Transplan-tation,” Transplantation Proceedings, Vol. 43, No. 3, 2011, pp. 749-750. doi:10.1016/j.transproceed.2011.01.104
[19] M. Ravaioli, et al., “Portal Vein Thrombosis and Liver Transplantation: Evolution during 10 Years of Experience at the University of Bologna,” Annals of Surgery, Vol. 253, No. 2, 2011, pp. 378-384. doi:10.1097/SLA.0b013e318206818b
[20] A. P. Ramos, et al., “Portal Vein Thrombosis and Liver Transplantation: Long Term,” Transplantation Proceed-ings, Vol. 42, No. 2, 2010, pp. 498-501. doi:10.1016/j.transproceed.2010.01.038

Copyright © 2024 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.