Mycobacterium tuberculosis in the aorta of a patient with takayasu’s arteritis. extra pulmonary tuberculosis

María Elena Soto, Virgilia Soto, Julia Isela Martín Sandría, Ricardo Gamboa, Claudia Huesca

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DOI: 10.4236/health.2011.33030                

Abstract

Takayasu’s arteritis (TA), of unknown etiology, has been related with Mycobacterium tuberculosis infection. The published cases are controversial. A 29- year-old man died, prolapse of the aortic valve and unspecific arteritis were demonstrated at necropsy. Our objective was to search in the fresh aortic tissues, the infectious agent of tuberculosis through culture, as well as by performing histopathology and searching by the molecular study, sequences of genes associated to micobacteria and Ziehl’s stain. Results. The bacillus of tuberculosis was observed by the Ziehl’s stain and the sequences of insertion IS6110 gene were identified. Our findings support the relation of TA with possible tuberculosis infection.Conclusion. The possibility that Takayasu’s arteritis is an extra pulmonary tu-berculosis must be explored.

Keywords

Takayasu’s arteritis, extrapulmonary tuberculosis, IS6110 and HupB sequences

Conflicts of Interest

The authors declare no conflicts of interest.

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