A Case of Carbapenem Resistant Non-K1/K2 Serotype Klebsiella pneumoniae Liver Abscess

Lucy Cheng, Leung Kristopher Siu, Tom Chiang

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Department of Medicine, Rutgers New Jersey Medical School, Newark, USA.

DOI: 10.4236/aid.2013.33032                

Abstract

Klebsiella pneumoniae liver abscess (KPLA) has been described as an invasive syndrome with extrahepatic complications. The majority of KPLA is caused by capsular serotype K1 and K2 isolates. We report a case of carbapenem resistant Klebsiella pneumoniae liver abscess. The patient initially presented with infected right above-the-knee amputation and was later found with a large liver abscess. Initial antimicrobial susceptibility showed carbapenem resistant K. pneumoniae (CRKP). Further molecular workup revealed that the isolate was a less virulent non-K1/K2 serotype, and both rmpA and kfu genes were negative. The lack of outer membrane porins likely contributed to the carbapenem resistance. To our knowledge, this is a first reported case of carbapenem resistant, non-K1/K2 serotype K. pneumoniae liver abscess in the United States.

Keywords

Liver Abscess; Klebsiella pneumoniae; Capsular Serotype; Carbapenem Resistance

Conflicts of Interest

The authors declare no conflicts of interest.

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