Effects of air pollution on the risk of acute myocardial infarction in Charleroi, Belgium

Abstract

Atmospheric pollution would increase morbidity and mortality rates for various respiratory illnesses in urban areas, and could also be an explanatory factor of higher rates of myocardial infarction in Charleroi compared with the other Belgian cities. The present study investigates the health effects of acute exposure to air pollution on cardiovascular morbidity/mortality in Charleroi. The study is based on comparing hospital data taken from the registry of ischaemic cardiopathies in Charleroi (1999 to 2008) to data on the air quality in this region. To measure the association between atmospheric pollution and the number of cases of myocardial infarction, Poisson regression was carried out. The excess risk of myocardial infarction was analysed according to the month of admission. For men, a decrease in the attack rate of myocardial infarction is visible during the first three years of the study, later to remain stable. For women, attack rates are stable throughout the study. Most of the pollutants vary according to season. Except for ozone, concentrations are generally higher in winter. We observe an association between the concentrations of PM10 and NO2 and morbidity/mortality by acute myocardial infarction. The increased risk for an increase of 10 μg/m3 of pollutant is 1.8% for PM10 and 4.0% for NO2. Multivariate models must still be developed and applied to our data.

Share and Cite:

Coppieters, Y. , Collart, P. , Mercier, G. , Massamba, V. , Bouland, C. and Levêque, A. (2013) Effects of air pollution on the risk of acute myocardial infarction in Charleroi, Belgium. Open Journal of Epidemiology, 3, 44-52. doi: 10.4236/ojepi.2013.32008.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] Bliefert, C. and Perraud, R. (2009) Chemistry of the environment: Air, water, soil, waste. De Boeck.
[2] Nemery, B., Hoet, P. and Nemmar, A. (2001) The Meuse Valley fog of 1930: An air pollution disaster. Lancet, 357, 704-708. doi:10.1016/S0140-6736(00)04135-0
[3] Peel, J.L., Metzger, K.B., Klein, M., Flanders, W.D., Mulholland, J.A. and Tolbert, P.E. (2007) Ambient air pollution and cardiovascular emergency department visits in potentially sensitive groups. American Journal of Epidemiology, 165, 625-633. doi:10.1093/aje/kwk051
[4] Pope 3rd, C.A., Thun, M.J., Namboodiri, M.M., Dockery, D.W., Evans, J.S., Speizer, F.E. and Heath Jr., C.W. (1995) Particulate air pollution as a predictor of mortality in a prospective study of US adults. American Journal of Respiratory and Critical Care Medicine, 151, 669-674. doi:10.1164/ajrccm/151.3_Pt_1.669
[5] Maheswaran, R., Haining, R.P., Brindley, P., Law, J., Pearson, T., Fryers, P.R., et al. (2005) Outdoor air pollution, mortality, and hospital admissions from coronary heart disease in Sheffield, UK: A small-area level ecological study. European Heart Journal, 26, 2543-2549. doi:10.1093/eurheartj/ehi457
[6] Bhaskaran, K., Hajat, S., Haines, A., Herrett, E., Wilkinson, P. and Smeeth, L. (2009) Effects of air pollution on the incidence of myocardial infarction. Heart, 95, 1746-1759. doi:10.1136/hrt.2009.175018
[7] Walloon Public Service (SPW) and the Walloon Agency for Air and Climate (AWAC) (2009) Networks monitoring of air quality. Scientific Institute of Public Service (ISSeP), Report, 40 p.
[8] Boldo, E., Medina, S., Le Tertre, A., Hurley, F., Mücke, H.G., Ballester, F., Aguilera, I., Eilstein, D. and Apheis Group (2006) Apheis: Health impact assessment of long-term exposure to PM2.5 in 23 European cities. European Journal of Epidemiology, 21, 449-458. doi:10.1007/s10654-006-9014-0
[9] Medina, S., Le Tertre, A. and Saklad, M. on Behalf of the Apheis Collaborative Network (2009) The Apheis project: Air pollution and health—A European information system. Air Quality, Atmosphere and Health, 2, 185-198. doi:10.1007/s11869-009-0050-2
[10] WHO Regional Office for Europe (1985) Targets for health for all. Copenhagen.
[11] Tunstall-Pedoe, H., Kuulasmaa, K., Amouyel P., Arveiler, D., Rajakangas, A.M. and Pajak, A. (1994) WHO MONICA Project. Myocardial infarction and coronary deaths in the World Health Organization. Circulation, 90, 583-612. doi:10.1161/01.CIR.90.1.583
[12] Coppieters, Y., Collart, P. and Levêque, A. (2012) Gender differences in acute myocardial infarction, twenty-five years registration. International Journal of Cardiology, 160, 127-132. doi:10.1016/j.ijcard.2011.04.012
[13] Public Service of Wallonia (2012) Executive management of agriculture, natural resources and environment. Dashboard of Walloon environment. http://etat.environnement.wallonie.be
[14] HEI Collaborative Working Group on Air Pollution, Poverty, and Health in Ho Chi Minh City, Le, T.G., Ngo, L., Mehta, S., Do, V.D., Thach, T.Q., Vu, X.D., Nguyen, D.T. and Cohen, A. (2012) Effects of short-term exposure to air pollution on hospital admissions of young children for acute lower respiratory infections in Ho Chi Minh City, Vietnam. Research Report (Health Effects Institute), 5-72.
[15] Deger, L., Plante, C., Jacques, L., Goudreau, S., Perron, S., Hicks, J., Kosatsky, T. and Smargiassi, A. (2012) Active and uncontrolled asthma among children exposed to air stack emissions of sulphur dioxide from petroleum refineries in Montreal, Quebec: A cross-sectional study. Canadian Respiratory Journal, 19, 97-102.
[16] Bhaskaran, K., Hajat, S., Armstrong, B., Haines, A., Herrett, E., Wilkinson, P. and Smeeth, L. (2011) The effects of hourly differences in air pollution on the risk of myocardial infarction: Case crossover analysis of the MINAP database. British Medical Journal, 343, d5531. doi:10.1136/bmj.d5531
[17] Rosenlund, M., Bellander, T., Nordquist, T. and Alfredsson, L. (2009) Traffic-generated air pollution and myocardial infarction. Epidemiology, 20, 265-271. doi:10.1097/EDE.0b013e318190ea68
[18] Devlin, R.B., Duncan, K.E., Jardim, M., Schmitt, M.T., Rappold, A.G. and Diaz-Sanchez, D. (2012) Controlled exposure of healthy young volunteers to ozone causes cardiovascular effects. Circulation, 126, 104-111.
[19] Nuvolone, D., Balzi, D., Chini, M., Scala, D., Giovannini, F. and Barchielli, A. (2011) Short-term association between ambient air pollution and risk of hospitalization for acute myocardial infarction: Results of the cardiovascular risk and air pollution in Tuscany (RISCAT) study. American Journal of Epidemiology, 174, 63-71. doi:10.1093/aje/kwr046
[20] Nawrot, T.S., Torfs, R., Fierens, F., De Henauw, S., Hoet, P.H., Van Kersschaever, G., De Backer, G. and Nemery, B. (2007) Stronger associations between daily mortality and fine particulate air pollution in summer than in winter: evidence from a heavily polluted region in western Europe. Journal of Epidemiology & Community Health, 61, 146-149. doi:10.1136/jech.2005.044263
[21] De Henauw, S., De Bacquer, D., de Smet, P., Kornitzer, M. and De Backer, G. (1999) Trends in coronary heart disease in two Belgian areas: Results from the MONICA Ghent-Charleroi study. Journal of Epidemiology & Community Health, 53, 89-98. doi:10.1136/jech.53.2.89

Copyright © 2024 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.