An evaluation of the arterial occlusions in peripheral arterial disease by 64-detector multi-slice CT angiography: DSA correlation

Abstract

Objective: Evaluation of peripheral arterial disease with 64-detector multi-slice CT angiography (MDCT- A) and comparison of the results with the results of digital subtraction angiography (DSA), a standard reference. Materials and Method: The written informed consent of the patients and ethics committee approval were obtained. The retrospective study group consisted of 28 patients with a diagnosis of peripheral arterial disease. Using 64-MDCT-A, the arterial tree of the lower extremity was evaluated for the presence of steno-occlusive lesions that might have led to luminal stenosis. The diagnostic reliability of 64-MDCT- A was calculated and compared with that of DSA. Findings: In the segment-based analysis, the sensitivity, specificity, and reliability rates of 64-MDCT angiography in determining significant stenoses were 97.7%, 97%, and 97.3%, respectively. The Kappa co-efficiency for compatibility between 64-MDCT-A and DSA methods in grading stenosis was calculated as 0.896 (P < 0.001) and it was statistically significant. Conclusion: 64-MDCT angiography is significantly compatible with DSA method in the evaluation of peripheral arterial diseases. It is a non-invasive method and can be an alternative to DSA.

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Oztekin, P. , Sonmez, A. , Kucukay, F. , Oztuna, D. , Sanlıdilek, U. and Kosar, U. (2013) An evaluation of the arterial occlusions in peripheral arterial disease by 64-detector multi-slice CT angiography: DSA correlation. World Journal of Cardiovascular Diseases, 3, 250-256. doi: 10.4236/wjcd.2013.32039.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] Garcia, L.A. (2006) Epidemiology and pathophysiology of lower extremity peripheral arterial disease. Journal of Endovascular Therapy, 13, 113-119. doi:10.1583/05-1751.1
[2] Ota, H., Takase, K., Rikimaru, H., Tsuboi, M., Yamada, T., Sato, A., et al. (2005) Quantitative vascular measurements in arterial occlusive disease. RadioGraphics, 25, 1141-1158. doi:10.1148/rg.255055014
[3] Rubin, G.D., Schmidt, A.J., Logan, L.J. and Sofilos, M.C. (2001) Multidetector row CT angiography of lower extremity arterial inflow and runoff. Initial experience. Radiology, 221, 146-158. doi:10.1148/radiol.2211001325
[4] Reimer, P. and Landwehr, P. (1998) Non-invasive vascular imaging of peripheral vessels. European Radiology, 8, 858-872. doi:10.1007/s003300050483
[5] Laswed, T., Rizzo, E., Guntern, D., Doenz, F., Denys, A., Schnyder, P., et al. (2008) Assessment of occlusive arterial disease of abdominal aorta and lower extremities arteries: Value of multidetector CT angiography using an adaptive acquisition method. European Radiology, 18, 263-272. doi:10.1007/s00330-007-0749-0
[6] Hiatt, M.D., Fleischmann, D., Hellinger, J.C. and Rubin, G.D. (2005) Angiographic imaging of the lower extremities with multidetector CT. Radiologic Clinics of North America, 43, 1119-1127. doi:10.1016/j.rcl.2005.08.008
[7] Ofer, A., Nitecki, S.S., Linn, S., Epelman, M., Fischer, D., Karram, T., et al. (2003) Multidetector CT angiography of peripheral vascular disease: A prospective comparison with digital subtraction angiography. American Journal of Roentgenology, 180, 719-724. doi:10.2214/ajr.180.3.1800719
[8] Schernthaner, R., Stadler, A., Lomoschitz, F., Weber, M., Fleischmann, D., Lammer, J., et al. (2008) Multidetector CT angiography in the assessment of peripheral arterial occlusive disease: Accuracy in detecting the severity, number, and length of stenoses. European Radiology, 18, 665671. doi:10.1007/s00330-007-0822-8
[9] Catalano, C., Fraioli, F., Laghi, A., Napoli, A., Bezzi, M., Pediconi, F., et al. (2004) Infrarenal aortic and lower-extremity arterial disease: Diagnostic performance of multidetector row CT angiography. Radiology, 231, 555-563. doi:10.1148/radiol.2312020920
[10] Martin, M.L., Tay, K.H., Flak, B., Fry, P.D., Doyle, D.L., Taylor, D.C. et al. (2003) Multidetector CT angiography of the arterial system and lower extremities: A prospective comparison with digital subtraction angiography. American Journal of Roentgenology, 180, 1085-1091. doi:10.2214/ajr.180.4.1801085
[11] Portugaller, H.R., Schoellnast, H., Hausegger, K.A., Tiesenhausen, K., Amann, W. and Berghold, A. (2004) Multislice spiral CT angiography in peripheral arterial occlusive disease: A valuable tool in detecting significant arterial lumen narrowing? European Radiology, 14, 16811687. doi:10.1007/s00330-004-2289-1
[12] Willmann, J.K., Baumert, B., Schertler, T., Wildermuth, S., Pfammatter, T., Verdun, F.R., et al. (2005) Aortoiliac and lower extremity arteries with 16-detector row CT angiography: Prospective comparison with digital subtraction angiography. Radiology, 236, 1083-1093. doi:10.1148/radiol.2362040895
[13] Albrecht, T., Foert, E., Holtkamp, R., Kirchin, M.A., Ribbe, C., Wacker, F.K., et al. (2007) 16-MDCT angiography aortoiliac and lower extremity arteries: Comparison with digital subtraction angiography. American Journal of Roentgenology, 189, 702-711. doi:10.2214/AJR.07.2333
[14] Ota, H., Takase, K., Igarashi, K., Chiba, Y., Haga, K., Saito, H., et al. (2004) MDCT compared with digital subtraction angiography for assessment of lower extremity arterial occlusive disease: Importance of reviewing crosssectional images. American Journal of Roentgenology, 182, 201-209. doi:10.2214/ajr.182.1.1820201
[15] Cernic, S., Mucelli, F.P., Pellegrin, A., Pizzolato, R. and Cova, M.A. (2009) Comparison between 64-row CT angiography and digital subtraction angiography in the lower extremities: Personal experience. La Radiologia Medica, 114, 1115-1129. doi:10.1007/s11547-009-0457-8
[16] Shareghi, S., Gopal, A., Gul, K., Matchinson, J.C., Wong, C.B., Weinberg, N., et al. (2010) Diagnostic accuracy of 64 mutidedector computed tomographic angiography in peripheral vascular disease. Catheterization and Cardiovascular Interventions, 75, 23-31.
[17] Fotiadis, N., Kyriakides, C., Bent, C., Vorvolakos, T. and Matson, M. (2011) 64-section CT angiography in patients with critical limb ischaemia and severe claudication: Comparison with digital subtractive angiography. Clinical Radiology, 66, 945-952. doi:10.1016/j.crad.2011.04.015
[18] Kock, M.C., Dijkshoorn, M.L., Pattynama, P.M. and Myriam Hunink, M.G. (2007) Multi-detector row computed tomography of peripheral arterial disease. European Radiology, 17, 3208-3222. doi:10.1007/s00330-007-0729-4

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