Endovascular Abdominal Aortic Aneurysm Repair under General Anesthesia Does Not Decrease Perioperative Myocardial Ischemic Events Compared with Open Repair

Abstract

Objectives: Endovascular abdominal aortic aneurysm repair (EVAR) is a common procedure for abdominal aortic aneurysm (AAA), based on minimal invasiveness compared with open surgical repair (OSR). However, general anesthesia can cause considerable perturbations in patients with AAA undergoing operative repair. The aim of this study was to compare the incidence of myocardial ischemic events in association with hemodynamic changes during EVAR and OSR under general anesthesia. Methods: We retrospectively reviewed the anesthetic and medical records of patients who underwent elective abdominal aortic aneurysm repair. ST segment changes on electrocardiography and hemodynamic changes were reviewed by the attending physicians. Results: Among 120 patients, EVAR and OSR were performed in 81 and 39 patients, respectively. There were no significant differences in preoperative morbidity between the two groups. The amount of estimated blood loss was significantly lower in EVAR than OSR. The incidence of ST segment changes in the two groups (EVAR: 16%, OSR: 23%) was not statistically different. ST segment changes occurred mainly postoperatively at resolution of anesthesia in EVAR, compared with intraoperatively in OSR. ST segment changes were mostly accompanied by tachycardia in EVAR patients, whereas they were associated with hypotension in OSR. Conclusion: Our results demonstrated a comparable incidence of perioperative ST segment changes under general anesthesia in EVAR and OSR. Patients who undergo EVAR and develop tachycardia are at risk of myocardial ischemia at resolution of anesthesia.

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N. Nanishi, K. Yamaura, K. Matsushita, K. Akiyoshi, Y. Karashima, M. Higashi and S. Hoka, "Endovascular Abdominal Aortic Aneurysm Repair under General Anesthesia Does Not Decrease Perioperative Myocardial Ischemic Events Compared with Open Repair," Open Journal of Anesthesiology, Vol. 3 No. 2, 2013, pp. 84-89. doi: 10.4236/ojanes.2013.32021.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] T. J. Wilt, F. A. Lederle, R. MacDonald, Y. C. Jonk, T. S. Rector and R. L. Kane, “Comparison of Endovascular and Open Surgical Repairs for Abdominal Aortic Aneurysm,” Evidence Report—Technology Assessment, Vol. 144, 2006, pp. 1-113.
[2] H. H. Feringa, S. Karagiannis, R. Vidakovic, P. G. Noordzij, J. J. Brugts, O. Schouten, M. R. vanSambeek, J. J. Bax and D. Poldermans, “Comparison of the Incidences of Cardiac Arrhythmias, Myocardial Ischemia, and Cardiac Events in Patients Treated with Endovascular versus Open Surgical Repair of Abdominal Aortic Aneurysms,” American Journal of Cardiology, Vol. 100, No. 9, 2007, pp. 1479-1484. doi:10.1016/j.amjcard.2007.06.043
[3] O. Schouten, V. H. van Waning, M. D. Kertai, H. H. Feringa, J. J. Bax, E. Boersma, A. Elhendy, E. Biagini, M. R. van Sanbeek, H. van Urk and D. Poldermans, “Perioperative and Long-Term Cardiovascular Outcomes in Patients Undergoing Endovascular Treatment Compared with Open Vascular Surgery for Abdominal Aortic Aneurysm or Iliaco-Femoro-Popliteal Bypass,” American Journal of Cardiology, Vol. 96, No. 6, 2005, pp. 861-866. doi:10.1016/j.amjcard.2005.05.036
[4] M. Prinssen, E. L. Verhoeven, J. Buth, P. W. Cuypers, M. R. van Sambeek, R. Balm, E. Buskens, D. E. Grobbee , J. D. Blankensteijn and Dutch Randomized Endovascular Aneurysm Management (DREAM) Trial Group, “A Randomized Trial Comparing Conventional and Endovascular Repair of Abdominal Aortic Aneurysms,” The New England Journal of Medicine, Vol. 351, No. 16, 2004, pp. 1607-1618. doi:10.1056/NEJMoa042002
[5] L. C. Brown, S. G. Thompson, R. M. Greenhalgh, J. T. Powell and Endovascular Aneu-rysm Repair Trial Participants, “Incidence of Cardiovascular Events and Death After Open or Endovascular Repair of Abdominal Aortic Aneurysm in the Randomized EVAR Trial 1,” British Journal of Surgery, Vol. 98, No. 7, 2011, pp. 935-942. doi:10.1002/bjs.7485
[6] EVAR Trial Participants, “Endovascular Aneurysm Repair and Outcome in Patients Unfit for Open Repair of Abdominal Aortic Aneurysm (EVAR Trial 2): Randomized Control Trial,” Lancet, Vol. 365, No. 9478, 2005, pp. 2187-2192. doi:10.1016/S0140-6736(05)66628-7
[7] M. V. Raval and M. K. Eskandari, “Outcomes of Elective Abdominal Aortic Aneurysm Repair among the Elderly: Endovascular versus Open Repair,” Surgery, Vol. 151, No. 2, 2012, pp. 245-260. doi:10.1016/j.surg.2010.10.022
[8] United Kingdom EVAR Trial Investigators, R. M. Green- halgh, L. C. Brown, J. T. Powell, S. G. Thompson, D. Epstein and M. J. Sculpher, “Endovascular versus Open Repair of Abdominal Aortic Aneurysm,” The New England Journal of Medicine, Vol. 362, No. 20, 2010, pp. 1863- 1871. doi:10.1056/NEJMoa0909305
[9] EVAR Trial Participants, “Endovascular Aneurysm Repair versus Open Repair in Patients with Abdominal Aortic Aneurysm (EVAR Trial 1): Randomised Controlled Trial,” Lancet, Vol. 365, No. 9478, 2005, pp. 2179-2186. doi:10.1016/S0140-6736(05)66627-5
[10] T. A. Winkel, O. Schouten, J. P. van Kuijk, H. J. Verha- gen, J. J. Bax and D. Poldermans, “Perioperative Asymptomatic Cardiac Damage after Endovascular Abdominal Aneurysm Repair Is Associated with Poor Long-Term Outcome,” Journal of Vascular Surgery, Vol. 50, No. 4, 2009, pp. 749-754. doi:10.1016/j.jvs.2009.04.069
[11] E. J. Bakker, K. M. van de Luijtgaarden, F. van Lier, T. M. Valentijn, S. E. Hoeks, M. Klimek, H. J. Verhangen and R. J. Stolker, “General Anaesthesia Is Associated with Adverse Cardiac Outcome after Endovascular Aneurysm Repair,” European Journal of Vascular & Endovascular Surgery, Vol. 44, No. 2, 2012, pp. 121-125. doi:10.1016/j.ejvs.2012.04.028
[12] P. W. Cuypers, M. Gardien, J. Buth, C. H. Peels, J. A. Charbon and W. C. Hop, “Randomized Study Comparing Cardiac Response in Endovascular and Open Abdominal Aortic Aneurysm Repair,” British Journal of Surgery, Vol. 88, No. 8, 2001, pp. 1059-1065. doi:10.1046/j.0007-1323.2001.01834.x
[13] The Study of Perioperative Ischemia Research Group, “Association of Peri-operative Myocardial Ischemia with Cardiac Morbidity and Mortality in Men Undergoing Non- Cardiac Surgery,” The New England Journal of Medicine, Vol. 323, No. 26, 1990, pp. 1781-1788. doi:10.1056/NEJM199012273232601
[14] P. Cao, S. Zannetti, G. Parlani, F. Verzini, S. Caporali, A. Spaccatini and F. Barzi, “Epidural Anesthesia Reduces Length of Hospitalization after Endoluminal Abdominal Aortic Aneurysm Repair,” Journal of Vascular Surgery, Vol. 30, No. 4, 1999, pp. 651-657. doi:10.1016/S0741-5214(99)70104-7
[15] J. P. Henretta, K. J. Hodgson, M. A. Mattos, L. A. Karch, S. N. Hurlbert, Y. Stern-bach, D. E. Rmsey and D. S. Sumner, “Feasibility of Endovascular Repair of Abdominal Aortic Aneurysms with Local Anesthesia with Intravenous Sedation,” Journal of Vascular Surgery, Vol. 29, No. 5, 1999, pp. 793-798. doi:10.1016/S0741-5214(99)70205-3
[16] C. De Virgilio, L. Romero, C. Donayre, K. Meek, R. J. Lewis, M. Lippmann, C. Rodriguez and R. White, “Endovascular Abdominal Aortic Aneurysm Repair with General versus Local Anesthesia: A Comparison of Cardiopulmonary Morbidity and Mortality Rates,” Journal of Vascular Surgery, Vol. 36, No. 5, 2002, pp. 988-991. doi:10.1067/mva.2002.128314
[17] J. R. Parra, T. Crabtree, R. B. McLafferty, J. Ayerdi, L. A. Gruneiro, D. E. Ramsey and K. J. Hodgson, “Anesthesia Technique and Outcomes of Endovascular Aneurysm Repair,” Annals of Vascular Surgery, Vol. 19, No. 1, 2005, pp. 123-129. doi:10.1007/s10016-004-0138-y
[18] V. Ruppert, L. J. Leurs, B. Steckmeier, J. Buth and T. Umscheid, “Influence of Anesthesia Type on Outcome after Endovascular Aortic Aneurysm Repair: An Analysis Based on Eurostar Data,” Journal of Vas-cular Surgery, Vol. 44, No. 1, 2006, pp. 16-21. doi:10.1016/j.jvs.2006.03.039
[19] V. Ruppert, L. J. Leurs, J. Rieger, B. Steckmeier, J. Buth, T. Umscheid and EUROSTAR Collaborators, “Risk-Adapted Outcome after Endovascular Aortic Aneurysm Repair: Analysis of Anesthesia Types Based on Eurostar Data,” Endovascular Aneurysm Repair, Vol. 14, No. 1, 2007, pp. 12-22. doi:10.1583/06-1957.1
[20] E. L. G. Verhoeven, C. S. Cina, I. F. J. Tielliu, C. J. Zeebregts, T. R. Prins, G. B. Eindhoven, M. M. Span, M. R. Kapma and J. J. van den Dungen, “Local Anesthesia for Endovascular Abdominal Aortic Aneurysm Repair,” Journal of Vascular Surgery, Vol. 42, No. 3, 2005, pp. 402- 409. doi:10.1016/j.jvs.2005.05.047
[21] Z. A. Ali, C. J. Callaghan, A. A. Ali, A. Y. Sheikh, A. Akhtar, A. Pavlovic, S. A. Nouraei, D. P. Dutka and M. E. Gaunt, “Perioperative Myocardial Injury after Elective Open Abdominal Aortic Aneurysm Repair Predicts Outcome,” European Journal of Vascular & Endovascular Surgery, Vol. 35, No. 4, 2008, pp. 420-421. doi:10.1016/j.ejvs.2007.10.007
[22] S. Garcia, J. E. Rider, T. E. Moritz, G. Pierpont, S. Goldman, G. C. Larsen, K. Shunk, F. Littooy, S. Santilli, J. Rapp, D. J. Reda, H. B. Ward and E. O. McFalls, “Preoperative Coronary Artery Revascularization and Long- Term Outcomes Following Abdominal Aortic Vascular Surgery in Patients with Abdominal Myocardial Perfusion Scans: A Subgroup Analysis of the Coronary Artery Re-vascularization Prophylaxis Trial,” Catheterization and Cardi-ovascular Interventions, Vol. 77, No. 1, 2011, pp. 134-141. doi:10.1002/ccd.22699
[23] G. Landesberg, M. Mosseri, D. Zahger, Y. Wolf, M. Perouansky, H. Anner, B. Drenger, Y. Hasin, Y. Berlatzky and C. Weissman, “Myocardial Infarction after Vascular Surgery: The Role of Prolonged, Stress-Induced, ST Depression-Type Ischemia,” Journal of the American College of Cardiology, Vol. 37, No. 7, 2001, pp. 1389-1345. doi:10.1016/S0735-1097(01)01265-7
[24] L. N. Diebel, M. P. Lange, F. Schneider, K. Mason, R. F. Wilson, L. Jacobs and M. S. Dahn, “Cardiopulmonary Complications after Major Surgery: A Role of Epidural Anesthesia?” Surgery, Vol. 102, No. 4, 1987, pp. 660- 666.
[25] M. S. Gold, D. DeCrosta, C. Rizzuto, R. R. Ben-Harari and S. Ramanathan, “The Effect of Lumbar Epidural and General Anesthesia on Plasma Catecholamines and Hemodynamics during Abdominal Aortic Aneurysm Repair,” Anesthesia & Analgesia, Vol. 78, No. 2, 1994, pp. 225-230. doi:10.1213/00000539-199402000-00006
[26] M. P. Yeager, D. D. Glass, R. K. Neff and T. Brinck- Johnsen, “Epidural Anesthesia and Analgesia in High Risk Surgical Patients,” Anesthesiology, Vol. 66, No. 6, 1987, pp. 729-736. doi:10.1097/00000542-198706000-00004
[27] S. Malik, O. Boyko, N. Atkar and W. F. Young, “A Comparative Study of MR Imaging Profile of Titanium Pedicle Screws,” Acta Radiologica, Vol. 42, No. 3, 2001, pp. 291-293. doi:10.1080/028418501127346846

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