Comparing Epidural Analgesia and ON-Q Infiltrating Catheters for Pain Management after Hepatic Resection

Abstract

Background and Objectives: Pain control after hepatic resection presents unique challenges as subcostal incisions, rib retraction, and diaphragmatic irritation can lead to significant pain. Both epidural analgesia and ON-Q catheters have been used for postoperative pain management after hepatic surgery, but to our knowledge have not been directly compared. Methods: The records of 143 patient between the ages 18 and 70 were reviewed who underwent hepatic resection by a single surgeon. Patients were categorized according to method of postoperative pain control. Average pain scores for both study groups were collected until POD#3. Results: Demographic data and the length of surgery were similar between the groups (all P > 0.05). On the day of surgery and POD#1, average pain scores for the epidural group were lower than the ON-Q group (P < 0.0001 and P = 0.0008 respectively). There was no difference in pain scores on POD #2 (P = 0.2369) or POD #3 (P = 0.2289). Conclusions: Epidural analgesia provides superior pain control on the day of surgery and POD#1 when compared to On-Q catheter with IV PCA. There was no difference in pain scores on POD#2 or POD#3. Future prospective randomized trials comparing these analgesic methods will be required to further evaluate enhanced recovery after hepatic surgery.

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J. Soliz, R. Gebhardt, L. Feng, W. Dong, M. Reich and S. Curley, "Comparing Epidural Analgesia and ON-Q Infiltrating Catheters for Pain Management after Hepatic Resection," Open Journal of Anesthesiology, Vol. 3 No. 1, 2013, pp. 3-7. doi: 10.4236/ojanes.2013.31002.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] P. Feltracco, M. L. Brezzi, S. Barbieri, E. Serra, M. Milevoj and C. Ori, “Epidural Anesthesia and Analgesia in Liver Resection and Living Donor Hepatectomy,” Transplantation Proceedings, Vol. 40, No. 4, 2008, pp. 1165-1168. doi:10.1016/j.transproceed.2008.03.108
[2] A. Page, B. Rostad, C. A. Staley, J. H. Levy, J. Park, M. Goodman, et al., “Epidural Analgesia in Hepatic Resection,” Journal of the American College of Surgeons, Vol. 206, No. 3, 2008, pp. 1184-1192. doi:10.1016/j.jamcollsurg.2007.12.041
[3] J. B. Cywinski, B. M. Parker, M. Xu and S. A. Irefin, “A Comparison of Postoperative Pain Control in Patients after Right Lobe Donor Hepatectomy and Major Hepatic Resection for Tumor,” Anesthesia & Analgesia, Vol. 99, No. 6, 2004, pp. 1747-1752. doi:10.1213/01.ANE.0000136423.17446.5D
[4] S. Basu, A. Tamijmarane, D. Bulters, J. K. Wells, T. G. John and M. Rees, “An Alternative Method of Wound Pain Control Following Hepatic Resection: A Preliminary Study,” HPB (Oxford), Vol. 6, No. 3, 2004, pp. 186-189. doi:10.1080/13651820410030844
[5] M. Ali, D. C. Winter, A. M. Hanly, C. O’Hagan, J. Kea eny and P. Broe, “Prospective, Randomized, Controlled Trial of Thoracic Epidural or Patient-Controlled Opiate Analgesia on Perioperative Quality of Life,” British Journal of Anaesthesia, Vol. 104, No. 3, 2010, pp. 292 297. doi:10.1093/bja/aeq006
[6] C. L. Wu, S. R. Cohen, J. M. Richman, A. J. Rowlingson, G. E. Courpas, K. Cheung, et al., “Efficacy of Postoperative Patient-Controlled and Continuous Infusion Epidural Analgesia versus Intravenous Patient-Controlled Analgesia with Opioids: A Meta-Analysis,” Anesthesiology, Vol. 103, No. 5, 2005, pp. 109-110. doi:10.1097/00000542-200511000-00023
[7] S. J. Dolin, J. N. Cashman and J. M. Bland, “Effectiveness of Acute Postoperative Pain Management: I. Evidence from Published Data,” British Journal of Anaesthesia, Vol. 89, No. 3, 2002, pp. 409-423.
[8] B. M. Block, S. S. Liu, A. J. Rowlingson, A. R. Cowan, J. A. Cowan Jr. and C. L. Wu, “Efficacy of Postoperative Epidural Analgesia: A Meta-Analysis,” JAMA, Vol. 290, No. 18, 2003, pp. 2455-2463. doi:10.1001/jama.290.18.2455
[9] H. Jorgensen, J. Wetterslev, S. Moiniche and J. B. Dahl, “Epidural Local Anaesthetics versus Opioid-Based Analgesic Regimens on Postoperative Gastrointestinal Paralysis, PONV and Pain after Abdominal Surgery,” Cochrane Database of Systematic Reviews, No. 4, 2000, Article ID: CD001893.
[10] H. Kehlet and J. B. Dahl, “Anaesthesia, Surgery, and Challenges in Postoperative Recovery,” Lancet, Vol. 362, No. 9399, 2003, pp. 1921-1928. doi:10.1016/S0140-6736(03)14966-5
[11] S. S. Liu and C. L. Wu, “Effect of Postoperative Analgesia on Major Postoperative Complications: A Systematic Update of the Evidence,” Anesthesia & Analgesia, Vol. 104, No. 3, 2007, pp. 689-702. doi:10.1213/01.ane.0000255040.71600.41
[12] J. R. Rigg, K. Jamrozik, P. S. Myles, B. S. Silbert , P. J. Peyton, R. W. Parsons, et al., “Epidural Anaesthesia and Analgesia and Outcome of Major Surgery: A Randomised Trial,” Lancet, Vol. 359, No. 9314, 2002, pp. 1276-1282. doi:10.1016/S0140-6736(02)08266-1
[13] E. Forastiere, M. Sofra, D. Giannarelli, L. Fabrizi and G. Simone, “Effectiveness of Continuous Wound Infusion of 0.5% Ropivacaine by On-Q Pain Relief System for Postoperative Pain Management after Open Nephrectomy,” British Journal of Anaesthesia, Vol. 101, No. 6, 2008, pp. 841-847. doi:10.1093/bja/aen309
[14] J. J. Pelton, J. P. Hoffman and B. L. Eisenberg, “Comparison of Liver Function Tests after Hepatic Lobectomy and Hepatic Wedge Resection,” The American Journal of Surgery, Vol. 64, No. 5, 1998, pp. 408-414.
[15] D. M. Stamenkovic, Z. B. Jankovic, G. J. Toogood, J. P. Lodge and M. C. Bellamy, “Epidural Analgesia and Liver Resection: Postoperative Coagulation Disorders and Epidural Catheter Removal,” Minerva Anestesiologica, Vol. 77, No. 7, 2008, pp. 671-679.
[16] R. Shontz, V. Karuparthy, R. Temple and T. J. Brennan, “Prevalence and Risk Factors Predisposing to Coagulopathy in Patients Receiving Epidural Analgesia for Hepatic Surgery,” Regional Anesthesia and Pain Medicine, Vol. 34, No. 4, 2009, pp. 308-311. doi:10.1097/AAP.0b013e3181ac7d00
[17] L. Weinberg, N. Scurrah, K. Gunning and L. McNicol, “Postoperative Changes in Prothrombin Time Following Hepatic Resection: Implications for Perioperative Analgesia,” Anaesthesia and Intensive Care, Vol. 34, No. 4, 2006, pp. 438-443.
[18] F. Shafiq, M. Hamid and K. Samad, “Complications and Interventions Associated with Epidural Analgesia for Postoperative Pain Relief in a Tertiary Care Hospital,” Middle East Journal of Anesthesiology, Vol. 20, No. 6, 2010, pp. 827-832.
[19] W. Schwenk and B. Schinkel “Perioperative Schmerzthe rapie,” Der Chirurg, Vol. 82, No. 6, 2011, pp. 539-556. doi:10.1007/s00104-010-2051-y
[20] W. Baulig, K. Maurer, O. M. Theusinger, V. Hinselmann, B. Baulig, D. R. Spahn, et al., “Continuous Elastomeric Pump-Based Ropivacaine Wound Instillation after Open Abdominal Aortic Surgery: How Reliable Is the Technique?” Heart Surgery Forum, Vol. 14, No. 1, 2011, pp. 51-58. doi:10.1532/HSF98.20101089
[21] A. Karthikesalingam, S. R. Walsh, S. R. Markar, U. Sadat, T. Y. Tang and C. M. Malata, “Continuous Wound Infusion of Local Anaesthetic Agents Following Colorectal Surgery: Systematic Review and Meta-Analysis,” World Journal of Gastroenterology, Vol. 14, No. 34, 2008, pp. 5301-5305. doi:10.3748/wjg.14.5301
[22] T. R. Yoost, M. McIntyre and S. J. Savage, “Continuous Infusion of Local Anesthetic Decreases Narcotic Use and Length of Hospitalization after Laparoscopic Renal Surgery,” Journal of Endourology, Vol. 23, No. 4, 2009, pp. 623-626. doi:10.1089/end.2008.0586

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