Biological effects of EV71 infection in neural cells

Xia Cao, Li-Chun Wang, Long-Ding Liu, Yun Liao, Cheng-Hong Dong, Qi-Han Li

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DOI: 10.4236/jbpc.2010.12014                

Abstract

Enterovirus 71 (EV71) can cause serious nervous system lesions but to date the pathogenesis has been unclear. Our results show that EV71 proliferates in the neural cells and leads to neural cell lesions. The study of the pathology of EV71 infection in neonatal rat brains shows that the invasive ability of EV71 to the nervous system in vivo may depend on many unknown factors.

Keywords

EV71; Neural Cell; Infection; Biological Effects

Conflicts of Interest

The authors declare no conflicts of interest.

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