A lightweight mainstream capnometer with very low dead space volume is useful monitor for neonates with spontanous and mechanical ventilation: Pilot study

Daijiro Takahashi, Miyu Matsui, Takehiko Hiroma, Tomohiko Nakamura

Division of Neonatology, Nagano Children’s Hospital, Nagano, Japan.

DOI: 10.4236/ojped.2012.22021                

Abstract

Objects: The purpose of this study was to observe a correlation between P_ETCO₂ and PaCO₂ in intubated neonates under intermittent mandatory ventilation with spontaneous breathing. Material and methods: A total of 55 paired P_ETCO₂ measured by mainstream capnometry and PaCO₂ values were obtained from 4 intubated neonates in our neonatal intensive care units at Nagano Children’s Hospital, Nagano, Japan. Results: P_ETCO₂ and PaCO₂ were significantly correlated (r² = 0.928, p < 0.0001). For samples in ventilated neonates with spontaneous breathing, maximum P_ETCO₂ and mean P_ETCO₂ correlated strongly with PaCO₂ (maximum P_ETCO₂: r² = 0.9401, p < 0.0001; mean P_ETCO₂: r² = 0.8587, p < 0.0001). Although PaCO₂ also correlated with minimum P_ETCO₂ (r² = 0.2884, p < 0.01) in ventilated infants with spontaneous breathing, a significant difference was seen with maximum P_ETCO₂ (p < 0.05) and mean P_ETCO₂ (p < 0.05) in the correlation coefficient r between PaCO₂ and P_ETCO₂. Conclusion: Present study showed that a good correlation exists between P_ETCO₂ and PaCO₂ in intubated neonates under intermittent mandatory ventilation with spontaneous breathing. Lightweight with low amounts of dead space mainstream capnometry can be used as noninvasive monitor in incubated neonates with spontaneous breathing.

Keywords

Capnography; Neonate

Conflicts of Interest

The authors declare no conflicts of interest.

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