Respiratory Epithelial Adenomatoid Hamartoma of the Nasal Cavity: A Case Report

R. P. S. Punia, Irneet Mundi, Arjun Dass, Harsh Mohan

Government Medical College & Hospital, Chandigarh, India.

DOI: 10.4236/ss.2012.33032                

Abstract

Respiratory epithelial adenomatoid hamartoma (REAH) is an uncommon lesion of the upper aerodigestive tract. It usually presents as a nasal or as a sinus or nasopharyngeal mass. The potential danger associated with REAH is the risk of misdiagnosis. Recognition and awareness of this benign lesion is necessary to distinguish it from inverted papilloma and adenocarcinoma. This is important to avoid aggressive surgery. We report a case of REAH diagnosed on histopathology.

Keywords

Respiratory Epithelial Adenomatoid Hamartoma; Hamartoma; Nasal Cavity

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1]	J. A. Ozolek, E. L. Barnes and J. L. Hunt, “Basal/ Myoepithelial Cells in Chronic Sinusitis, Respiratory Epithelial Adenomatoid Hamartoma, Inverted Papilloma and Intestinal Type and Non Intestinal Type Sinonasal Adenocarcinoma: An Immunohistochemical Study,” Archives of Pathology and Laboratory Medicine, Vol. 131, No. 4, 2007, pp. 530-537.
[2]	V. A. Fitzhugh and N. Mirani, “Respiratory Epithelial Adenomatoid Hamartoma: A Review,” Head and Neck Pathology, Vol. 2, No. 3, 2008, pp. 203-208. doi:10.1007/s12105-008-0064-3
[3]	B. M. Weing and D. K. Heffner, “Respiratory Epithelial Adenomatoid Hamartomas of the Sinonasal Tract and Nasopharynx: A Clinicopathologic Study of 31 Cases,” Annals of Otology, Rhinology, and Laryngology, Vol. 104, 1995, pp. 639-645.
[4]	R. D. Carlo, R. Rinaldi, G. Ottaviano and G. Pastore, “Respiratory Epithelial Adenomatoid Hamartoma of the Maxillary Sinus: A Case Report,” Acta Otorhinolaryngologica Italica, Vol. 26, 2006, pp. 225-227.
[5]	C. Delbrouck, S. F. Aguilar, G. Choufani and S. Hassid, “Respiratory Epithelial Adenomatoid Hamartoma Associated with Nasal Polyposis,” American Journal of Otolaryngology, Vol. 25, No. 4, 2004, pp. 282-284. doi:10.1016/j.amjoto.2004.02.005
[6]	L. Barnes, “Schneiderian Papillomas and Nonsalivary Glandular Neoplasms of the Head and Neck,” Modern Pathology, Vol. 15, No. 3, 2001, pp. 279-297. doi:10.1038/modpathol.3880524
[7]	W. F. Ingram, M. C. Noone and M. B. Gillespie, “Respiratory Epithelial Adenomatoid Hamartoma: A Case Report,” Ear, Nose & Throat Journal, Vol. 85, No. 3, 2006, pp. 190-192.
[8]	Z. Cao, Z. Gu, J. Yang and M. Jin, “Respiratory Epithelial Hamartoma of Bilateral Olfactory Clefts Associated with Nasal Polyposis: Three Cases Report and Literature Review,” Auris Nasus Larynx, Vol. 37, No. 3, 2010, pp. 352-356. doi:10.1016/j.anl.2009.10.003
[9]	J. G. Seol, V. A. Livolsi, B. W. O’Malley Jr., J. Y. Chen and L. A. Loevner, “Respiratory Epithelial Hamartoma of Bilateral Olfactory Recesses: A Neoplastic Mimic?” AJNR, Vol. 31, 2010, pp. 277-279. doi:10.3174/ajnr.A1755