Urodynamic Abnormalities in Patients with Relapsing Remitting Multiple Sclerosis ()
ABSTRACT
Background: Multiple sclerosis (MS) is a disease with wide
variability in clinical presentation. Bladder dysfunctions are very common in
MS patients. Early detection of
bladder abnormalities is important to improve the outcome in MS patients. Objectives: The aim of this study is to evaluate the urodynamic detected bladder
dysfunctions in relapsing remitting MS patients with mild or without lower urinary tract symptoms. Methods: This is a prospective study for 32
patients with relapsing remitting Multiple Sclerosis from January 2017 to June
2018. We included patients with mild or without lower urinary tract symptoms
(LUTS) who had mild to moderate disability. Urodynamic studies were performed
for all patients. Results: Urodynamic abnormalities were detected in 22 patients (68.75%). Detrusor
overactivity (DO) was present alone in 8 patients (25%); DO combined with
detrusor external sphincter dyssynergia in 8 patients (25%); DO with low
compliant bladder and impaired contractility in another 4 patients (13%) while
DO with low complaint bladder in 2 patients (6%). Bladder dysfunction was
correlated to high disability score; longer duration of illness; frequent relapses
and the presence of LUTS. Conclusion: Urodynamic abnormalities were found in 68.75% of our patients. This highlights the importance of urodynamic studies in the early
evaluation of relapsing remitting Multiple Sclerosis.
Share and Cite:
Bekhit, A. and Saber-Khalaf, M. (2018) Urodynamic Abnormalities in Patients with Relapsing Remitting Multiple Sclerosis.
World Journal of Neuroscience,
8, 423-431. doi:
10.4236/wjns.2018.84033.
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