Author(s)

Anwar Ali Jamali^1*, Jawaid Hussain Lighari², Shamasddin Shaikh¹, Ghulam Mustafa Jamali¹, Bhojo Mal Tanwani³, Muhammad Aslam Channa⁴, Ameer Ali Jamali⁵, Muhammad Ali Suhail⁶

¹Department of Medicine, Peoples University of Medical and Health Sciences, Nawabshah, Pakistan.
²Department of Community Medicine, Peoples University of Medical and Health Sciences, Nawabshah, Pakistan.
³Department of Physiology, Peoples University of Medical and Health Sciences for Women, Nawabshah, Pakistan.
⁴Department of Anatomy, Gambat Institute of Medical Sciences, Khairpur, Pakistan.
⁵Department of Peadiatrics, Peoples University of Medical and Health Sciences for Women, Nawabshah, Pakistan.
⁶Department of Surgery, Peoples University of Medical and Health Sciences for Women, Nawabshah, Pakistan.

Background: A relationship among vitamin D and pulmonary tuberculosis. Objective: To conclude the occurrence of Vitamin D insufficiency in subjects suffering from pulmonary TB. Design: This was a cross sectional study. Setting: Current study was performed at department of medicine, Peoples Medical College Hospital Nawabshah starting from January 2017 to December 2017. Samples: 385 AFB positive subjects of pulmonary tuberculosis after achieving the criteria of selection were recruited. Material and Methods: After a brief discussion, the patients were characterized for variable evaluation such as age, gender, sputum AFB and duration of disease and presence of low vitamin D levels. Sputum AFB criterion was used for Data collection. Fasting blood samples were collected for analysis of vitamin D levels in all subjects of AFB positive pulmonary tuberculosis. Results: In 385 diagnosed patients with smear positive PTB, 273 (70.9%) males and 112 (29.1%) were female. Vitamin D levels were within normal or sufficient range in 134 (34.8%), below normal range in 251 (65.2%) cases (insufficient in 09.56% (24/251) and deficient in 90.43% (227/251) cases). Conclusion: Decreased levels of vitamin D were common in subjects with AFB smear Positive PTB cases.

Pulmonary Tuberculosis, Vitamin D, Vitamin D Insufficiency, 25-Hydroxyvitamin D

Jamali, A. , Lighari, J. , Shaikh, S. , Jamali, G. , Tanwani, B. , Channa, M. , Jamali, A. and Suhail, M. (2018) Vitamin D: Level of Vitamin D3 in AFB Positive PTB Patients in Initial Diagnostic Phase. Journal of Tuberculosis Research, 6, 251-269. doi: 10.4236/jtr.2018.64023.