Prevalence of Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency in India: A Systematic Review - Advances in Bioscience and Biotechnology

ABB > Vol.9 No.9, September 2018

Advances in Bioscience and Biotechnology

Volume 9, Issue 9 (September 2018)

ISSN Print: 2156-8456 ISSN Online: 2156-8502

Google-based Impact Factor: 1.18 Citations h5-index & Ranking

Prevalence of Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency in India: A Systematic Review ()

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Download as PDF (Size: 829KB) PP. 481-496

DOI: 10.4236/abb.2018.99033 1,961 Downloads 5,863 Views Citations

Author(s)

I. I. Shah¹, J. Jarullah², B. Jarullah^1*

Affiliation(s)

¹Department of Biotechnology, Kadi Sarva Vishwavidyalaya, Gandhinagar, India.
²King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.

ABSTRACT

Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency is the most common enzyme deficiency of human erythrocyte affecting more than 400 million people worldwide. In India, G6PD deficiency was first reported in 1963 and since then various investigations have been conducted across country. The objective of this work was to study the prevalence of G6PD deficiency in different ethnic, caste and linguistic groups of Indian population. A systematic search of published literature was undertaken and the wide variability of G6PD deficiency has been observed ranging from 0% - 30.7% among the different caste, ethnic, and linguistic groups of India. It was observed that the incidence of G6PD deficiency was found to be considerably higher among the tribes (9.86%) as compared to other ethnic groups (7.34%) and significantly higher in males as compared to females.

KEYWORDS

Glucose-6-Phosphate Dehydrogenase, G6PD, Deficiency, India, Prevalence

Share and Cite:

Shah, I. , Jarullah, J. and Jarullah, B. (2018) Prevalence of Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency in India: A Systematic Review. Advances in Bioscience and Biotechnology, 9, 481-496. doi: 10.4236/abb.2018.99033.

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