Author(s)

Ryuta Washio, Masaya Takahashi, Sohsaku Yamanouchi, Masato Hirabayashi, Kenji Mine, Yukihiro Noda, Eriko Kanda, Atsushi Ohashi, Hirohide Kawasaki^*, Kazunari Kaneko

Department of Pediatrics, Kansai Medical University, Osaka, Japan.

Several patients with Down syndrome complicated by transient myeloproliferative disorder may develop liver cirrhosis for which no effective therapeutic agent exists. We report the infant with Down syndrome complicated by transient myeloproliferative disorder and liver cirrhosis who was successfully treated by Inchinkoto, the Japanese herbal medicine. In the present case, Inchinkoto appeared to prevent both histological and serological aggravation of liver cirrhosis. To the best of our knowledge, this is the first report of preventive effect of Inchinkoto on liver cirrhosis, and it can be a choice of treatment for infants with Down syndrome complicated by liver cirrhosis.

Inchinkoto, Transient Myeloproliferative Disorder, Down Syndrome, Liver Fibrosis, Japanese Herbal Medicine

Washio, R. , Takahashi, M. , Yamanouchi, S. , Hirabayashi, M. , Mine, K. , Noda, Y. , Kanda, E. , Ohashi, A. , Kawasaki, H. and Kaneko, K. (2017) Efficacy of Inchinkoto for Liver Cirrhosis in an Infant with Down Syndrome Complicated by Transient Myeloproliferative Disorder. Open Journal of Pediatrics, 7, 26-31. doi: 10.4236/ojped.2017.71004.