“Natural Site-Directed Mutagenesis” Might Exist in Eukaryotic Cells - Open Access Library Journal

OALibJ > Vol.3 No.4, April 2016

Open Access Library Journal

Volume 3, Issue 4 (April 2016)

ISSN Print: 2333-9705 ISSN Online: 2333-9721

Google-based Impact Factor: 0.73 Citations

“Natural Site-Directed Mutagenesis” Might Exist in Eukaryotic Cells ()

HTML XML

Download as PDF (Size: 230KB) PP. 1-5

DOI: 10.4236/oalib.1102595 714 Downloads 1,430 Views Citations

Author(s)

Gao-De Li

Affiliation(s)

Chinese Acupuncture Clinic, Liverpool, UK.

ABSTRACT

Site-directed mutagenesis refers to a man-made molecular biology method that is used to make genetic alterations in the DNA sequence of a gene of interest. But based on our recently published experimental findings, we propose that “natural site-directed mutagenesis” might exist in eukaryotic cells, which is triggered by harmful agents and co-directed by special transcription hotspots and mutation-contained intranuclear primers.

KEYWORDS

Natural Site-Directed Mutagenesis, Genetic Alteration, Mutation, CAGFs, DNA to DNA Transcription, Drug Resistance, Evolution of Eukaryotes, Antibody Diversity, Somatic Hypermutation

Share and Cite:

Li, G. (2016) “Natural Site-Directed Mutagenesis” Might Exist in Eukaryotic Cells. Open Access Library Journal, 3, 1-5. doi: 10.4236/oalib.1102595.

Cited by

No relevant information.

Journals Menu