Author(s)

Ryo Ishida^1,2*, Kazumi Komaki^1,2, Tetsuro Kusaba^1,2, Tsuneyuki Nakanouchi¹

¹Japanese Red Cross Kyoto Daiichi Hospital, Kyoto, Japan.
²Division of Nephrology, Department of Medicine, Kyoto Prefecture University of Medicine, Kyoto, Japan.

A 59-year-old man, who was treated for schizophrenia and psoriasis vulgaris with risperidone and cyclosporine, presented with high fever and myalgia. Those did not respond to treatment for neuroleptic malignant syndrome for two weeks, and multiple organ dysfunction developed, so he was admitted to our hospital, but died two days later. Autopsy detected the hemophagocytosis, Epstein Barr Virus (EBV)-reactivated cells, and the absence of glomerulonephritis and interstitial tubulitis. We considered that hemophagocytic syndrome (HPS) and myalgia were caused by reactivated EBV and the viremia under immunosuppression, and renal failure was caused by sepsis-like state by cytokine storm of HPS.

Hemophagocytic Syndrome, Epstein Barr Virus, Acute Kidney Injury

Ishida, R. , Komaki, K. , Kusaba, T. and Nakanouchi, T. (2016) Acute Kidney Injury with Epstein Barr Virus-Associated Hemophagocytic Syndrome. Case Reports in Clinical Medicine, 5, 233-237. doi: 10.4236/crcm.2016.57042.