Author(s)

Alice S. Ferng^1,2,3,4, Katherine M. Marsh^1,2,5, Tia R. Pilikian⁶, Alana Connell^1,2, Courtney Hemphill^1,7, Samata Paidy^5,8, Ray Runyan³, John Konhilas⁷, Zain Khalpey^{1,2,3,4,7,8,9*}

¹Department of Surgery, Division of Cardiothoracic Surgery, University of Arizona, Tucson, AZ, USA.
²College of Medicine-Tucson, University of Arizona, Tucson, AZ, USA.
³Department of Physiological Sciences, University of Arizona, Tucson, AZ, USA.
⁴Department of Biomedical Engineering, University of Arizona, Tucson, AZ, USA.
⁵Banner-University Medical Center, Tucson, AZ, USA.
⁶Amnio Technology LLC, Phoenix, AZ, USA.
⁷Department of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ, USA.
⁸Department of Anesthesia, University of Arizona, Tucson, AZ, USA.
⁹Department of Medical Imaging, University of Arizona, Tucson, AZ, USA.

Hospital inquired post-operative infections are a leading cause of morbidity and mortality in patients receiving left ventricular assist devices. We present the case of a patient who acquired Candida albicans and Staphylococci infections following left ventricular assist device implantation. Use of standard antibiotics caused the infection to worsen, thus an amniotic membrane patch was used as a last-resort treatment. Within 6 weeks of the amniotic membrane patch treatment, the infection resolved, the wound appeared exceptionally clean upon inspection, and granulation tissue was present. After the infection resolved, a successful latissimusdorsi tissue flap procedure was completed and the patient made a full recovery.

Antimicrobial, Amniotic Membrane, Ventricular Assist Device

Ferng, A. , Marsh, K. , Pilikian, T. , Connell, A. , Hemphill, C. , Paidy, S. , Runyan, R. , Konhilas, J. and Khalpey, Z. (2016) Human Amniotic Membrane Promotes Antimicrobial Microenvironment in a Device-Related Infection. Journal of Biomedical Science and Engineering, 9, 122-126. doi: 10.4236/jbise.2016.92008.