Author(s)

Nikhath Fathima, Mohamed Ziaulla, Afshan Banu, Shridhar Ishwar Panchamukhi, Imtiyaz Ahmed Khazi, Noor Shahina Begum

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The Preparation of 9-Methyl-3-thiophen-2-yl-thieno [3, 2-e] [1, 2, 4] triazolo [4, 3-c] pyrimi-dine-8-carboxylic acid ethyl ester is described. Elemental analysis, IR spectrum, ¹H NMR, ¹³C NMR and X-ray crystal structure analyses were carried out to determine the composition and molecular structure of the title compound. There are two independent molecules in the asymmetric unit exhibiting intermolecular C-H…N, C-H…O interactions with additional π-π interaction that further helps in stabilizing the supramolecular structure. The results showed that the proposed method for synthesis is simple, precise and accurate which was further confirmed by crystal structure analysis.

Thieno-Triazolo-Pyrimidine Derivative, Characterization, X-Ray Crystallographic Analysis, C-H…N, C-H…O and π-π Weak Interactions

N. Fathima, M. Ziaulla, A. Banu, S. Panchamukhi, I. Khazi and N. Begum, "Synthesis, Spectroscopy and X-Ray Crystal Structure of 9-Methyl-3-Thiophen-2-Yl-Thieno [3, 2-e] [1, 2, 4] Triazolo [4, 3-c] Pyrimidine-8-Carboxylic Acid Ethyl Ester," American Journal of Analytical Chemistry, Vol. 2 No. 3, 2011, pp. 371-375. doi: 10.4236/ajac.2011.23045.