Photofission enables a unique capability for the domain of non-chemical space propulsion. An ultra-intense laser enables the capacity to induce nuclear fission through the development of bre- msstrahlung photons. A fundamental architecture and performance analysis of a photofission pulsed space propulsion system through the operation of an ultra-intense laser is presented. A historical perspective of previous conceptual nuclear fission propulsion systems is addressed. These applications use neutron derived nuclear fission; however, there is inherent complexity that has precluded further development. The background of photofission is detailed. The conceptual architecture of photofission pulsed space propulsion and fundamental performance parameters are established. The implications are the energy source and ultra-intense laser can be situated far remote from the propulsion system. Advances in supporting laser technologies are anticipated to increase the potential for photofission pulsed space propulsion. The fundamental performance analysis of the photofission pulsed space propulsion system indicates the architecture is feasible for further evaluation.