Author(s)

Riccardo Rossi, Torello Lotti, Nicola Bruscino

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Photodynamic therapy (PDT) shows great efficacy and high tolerability for the treatment of non-melanoma skin cancer (actinic keratosis, basal cell carcinoma, Bowen’s disease) especially in patients with large and multiple lesions, in poor-healing sites and patients immunosuppressed or with co-morbidities. Besides, more recently, PDT has been used, widely and with great success, for many off-label diseases and in cosmetic dermatology, especially on photorejuvenation, therefore further and larger prospective studies with long-term follow-up are required to verify its efficacy and safety in treating these condition. The treatment of ageing skin remains a very hot topic, and many systems have been reported as having varying degrees of success. Nowadays our experience and literature data show how topical PDT can be considered a new non-invasive device for the treatment o photoaging skin with no/minimal side effects and able to bridge the world of medical and cosmetic dermatologic surgery.

Photodynamic Therapy, Nonablative Skin Rejuvenation, Actinic Keratosis, Field Cancerization, Dermatology

R. Rossi, T. Lotti and N. Bruscino, "Photodynamic Therapy/Assisted Photorejuvenation," Journal of Cosmetics, Dermatological Sciences and Applications, Vol. 1 No. 2, 2011, pp. 30-35. doi: 10.4236/jcdsa.2011.12005.