Diabetic Renal-Retinal Syndrome and Inflammatory Markers of Acute Phase ()
ABSTRACT
Objective: To determine
the association between the acute inflammatory markers and Diabetic
Renal-Retinal Syndrome in our patients. Methods: A total of 44 patients were
included in this transverse (cross sectional), observational, analytical, and
comparative study. Two groups of patients were created. Results: In patients
with chronic renal failure, stages 3, 4, or 5 (scale 1 to 5) were identified and
divided into two groups: Group I (Patients with concomitant diabetic
retinopathy stabilized with photocoagulation) 22 patients. Group II (Patients
with progression of retinopathy, after photocoagulation, in the form of
intraocular bleeding) 22 patients. The number of patients with chronic renal
failure in stage 3 was: Group I; 16. In Group II; 12 patients (OR: 1.0). Stage
4: Group I; 4 patients. Group II: 3 patients (OR: 1.0, CI 95%; 0.3843 - 2.021).
Stage 5: Group I; 2 patients. Group II; 7 patients (OR: 1.8148, CI 95%; 1.0448
- 3.1523; Chi-squared (x2) 2.7450,
p = 0.097). t-Test
found statistical significance in Erythrocyte Sedimentation Rate (ESR): p <
0.0001 (CI 95%; 7.8959 - 23.2515); R = 0.56 p = 0.001; and OR = 1.959 (CI 95%;
1.193 - 3.217). By non-parametric tests, C-reactive protein with binomial test
showed p < 0.001. ESR showed p < 0.001 with U of Mann Whitney.
Conclusions: With this study revealed a possible association of inflammatory
markers with Diabetic Renal-Retinal Syndrome.
Share and Cite:
Sepúlveda-Cañamar, F. , Hernández, R. , Baéz, J. and Cortés, J. (2014) Diabetic Renal-Retinal Syndrome and Inflammatory Markers of Acute Phase.
Journal of Diabetes Mellitus,
4, 194-201. doi:
10.4236/jdm.2014.43028.
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