Psychological and social wellbeing of patients diagnosed with coronary heart disease is an important component in patients’ recovery. The purpose of this study is to explore the psychological and social factors among individuals diagnosed with coronary artery disease. Methods: 164 patients diagnosed with CHD filled and returned a self administered. Data were collected in regard to stress, depression, perceived social support, and coping. Results: The analysis showed that patients who have moderate level of stress, perceived social support, mild level of depression, have more tendencies to use effective coping strategies. Also the analysis showed that cope, psychological distress, and perceived social support were significant predictors of high level of depression (F = 5.2, p < .001), and that perceived social support from others was the most significant protective factors against depression (F =12.7, p < .001). Conclusion: Mental health care providers need to consider their patients’ psychological wellbeing and sources of social support as part of their routine care and assessment.